Effective medicine part compatibility composition for preventing and treating diabetics and vascular diseases of diabetics

Abstract

The invention provides an effective medicine part compatibility composition for preventing and treating diabetics and vascular diseases of diabetics. The effective medicine part compatibility composition is prepared from the following effective parts of rehmannia glutinosa and dogwood in weight proportions: 2-3 parts of total iridoid glycoside extract of rehmannia glutinosa, 3-5 parts of total iridoid glycoside of dogwood and, 0.5-1.5 parts of total triterpenes acid extract of dogwood. The research result of an STZ-induced C57BL / 6 mouse diabetic model shows that the composition can remarkably improve the symptoms of 'three excessiveness and one insufficiency' of a diabetic mouse, can reduce the blood sugar value, can improve secretion of insulin, can reduce serum creatinine, urea nitrogen and AGEs levels, can improve discharge of urine creatinine, can reduce discharge of urine protein, and can improve pathological change of pancreas, kidneys, testis and hearts. The composition has the function of reducing blood sugar and ascular diseases of diabetics.

Description

technical field [0001] The invention relates to an effective part composition of traditional Chinese medicine, in particular to an effective part compatible composition for preventing and treating diabetes and its vascular diseases. Background technique [0002] In recent years, the number of Diabetes Mellitus (DM) patients has increased rapidly, becoming the third major disease that seriously threatens human life and health after tumors and cardiovascular and cerebrovascular diseases. As we all know, the terrible thing about diabetes is not its superficial symptoms of "more than three and one less". Its subsequent complications are the main cause of death and disability in diabetes. The nature of vascular disease is atherosclerosis, which mainly involves large blood vessels such as aorta and coronary artery, while diabetic microangiopathy is a chronic vascular complication unique to diabetes, mainly manifested as microangiopathy of kidney and testis. Diabetic vascular dise...

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Problems solved by technology

Therefore, judging from the current treatment status, the treatment of diabetic vascular disease by Western medicine is still in the exploratory stage, and no effective drug has been found yet.

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