Measurement device and method of female urine sodium predicted value

A measuring device and predictive value technology, applied in the field of medicine, can solve the problems of patient inconvenience, long urine collection time, salt evaluation, etc., and achieve the effect of simple measurement

Active Publication Date: 2018-04-17
PEOPLES HOSPITAL PEKING UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

24-hour urine sodium measurement is the most reliable and accurate method at present, but the 24-hour urine collection time is long and the process is cumbersome, which brings a lot of inconvenience to patients
Therefore, it is extremely important to establish a simple, convenient and effective salt intake assessment method to guide the government, scholars and people to carry out precise salt restriction. Unfortunately, there is no good method to assess salt intake at present

Method used

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  • Measurement device and method of female urine sodium predicted value
  • Measurement device and method of female urine sodium predicted value
  • Measurement device and method of female urine sodium predicted value

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] Establishment of the inventive method

[0045]The data come from hypertensive patients aged 15-90 who were hospitalized in the hypertension ward of Peking University People's Hospital from August 2011 to January 2016. If the research subject is accompanied by severe multi-system diseases (such as rheumatic immune diseases and tumors) and secondary hypertension, combined with severe liver and kidney diseases, infection, tumors, malnutrition, severe heart and kidney insufficiency in the past 6 months, Cardiovascular and cerebrovascular events (myocardial infarction, stroke), hypertensive emergencies, use of glucocorticoids, use of diuretics or single-tablet compound preparations containing diuretics within the past month, or 24-hour urine output less than 500ml, failed to collect completely Those with urine will be excluded.

[0046] Record the age, gender, smoking and drinking status of all the selected personnel when they were admitted to the hospital, collect informat...

Embodiment 2

[0067] Embodiment 2, verification of the inventive method

[0068] The information of the research subjects was substituted into the Kawasaki formula, and together with the predicted value calculated by the newly developed SUN3 formula, it was compared with the measured value of 24h urine sodium.

[0069] The verification process is mainly reflected in the following aspects:

[0070] 1) Comparison of mean and correlation

[0071] 2) Comparison of accuracy: Accuracy is defined as the percentage of the predicted value falling within ±15%, ±30%, ±50% of the measured value, recorded as P15, P30, and P50 respectively

[0072] Comparison of Consistency: Evaluation by Bland-Altman Plot.

[0073] Comparison of judging excessive urinary sodium: In order to evaluate the sensitivity and specificity of the three methods for predicting whether urinary sodium excretion exceeded the standard (i.e. >100mmol / d), the ROC curve was made with the measured urinary sodium 100mmol / d as the cut-off...

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Abstract

The invention provides a measurement device and method of 24h female urine sodium predicted value. The measurement device comprises a urine component amount detection unit and a 24h urine sodium predicted value calculation unit, wherein the urine component amount detection unit is used for detecting a component amount in point urine in the point urine urinated within a specified period and the component amount comprises point urine sodium value, point urine potassium value and point urine creatinine value; the 24h urine sodium predicted value calculation unit is used for calculating the 24h urine sodium predicted value of the female in people according to the component amount in the point urine. By adopting the device provided by the invention, the 24h urine sodium value of the female canbe measured in a high-precision, time-saving and convenient manner.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a measuring device and method for evaluating the predictive value of 24-hour urine sodium in women. Background technique [0002] Excessive salt intake can lead to high blood pressure, and high blood pressure is an important risk factor for coronary heart disease and stroke. According to WHO statistics, about 54% of stroke and 47% of ischemic heart disease deaths are related to high blood pressure . Sodium intake was significantly positively correlated with blood pressure levels. Excessive intake of sodium salt will increase plasma volume and increase blood pressure. At the same time, high intake of sodium salt will also cause sodium to deposit on the blood vessel wall and aggravate arteriosclerosis and atherosclerosis, resulting in increased blood pressure and the risk of major vascular disease events. occurred (coronary heart disease and stroke). Hypertension has become a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/48G01N33/493G01N33/70
CPCG01N33/48G01N33/493G01N33/70
Inventor 孙宁玲王鸿懿袁亦芳牟建军姜一农孙跃民徐新娟商黔惠初少莉尹新华王浩袁洪崔玉贤
Owner PEOPLES HOSPITAL PEKING UNIV
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