Improving symmetry in brain scans

Abstract

A system and method including adapting a symmetric model representing anatomical structures of the brain, the model corresponding to a brain scan image, transforming first and second points provided on first and second hemispheres of the brain and computing, based on the transformation, a patient- specific symmetric anatomical model of the brain.

Description

Background technique [0001] In neurology, many applications of quantitative imaging involve information on the relative location of the left and right hemispheres of the brain. Region-of-interest (ROI)-based comparisons between the left and right hemispheres of the brain can play an important role in a variety of imaging modalities and clinical questions. Typically, these applications utilize corresponding parts of the left and right hemispheres, for example to compare anatomy and make appropriate diagnoses. These applications reflect the position relative to the mid-sagittal plane that divides the left and right hemispheres. Using image analysis techniques, brain scans are oriented such that the midsagittal plane maps to a predefined position P on the x-axis. Corresponding points in the left and right hemispheres are then identified via the x-axis component of the point reflected on P. These applications generally assume that the brain is symmetric with respect to the mids...

AI Technical Summary

Problems solved by technology

However, many registration techniques limit the types of deformations that can be done via parameterization (e.g. b-splines or linear transformations) and cannot remove brain asymmetry due to possible deformations that do not match the brain's anatomy

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