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Dual-ring resonant cavity-based Mach-Zehnder interferometer optical biosensor

A double-ring resonant cavity and biosensor technology, applied in the field of optical biosensors, can solve problems such as poor interference effects, achieve high integration, reduce costs, and ensure interference effects

Active Publication Date: 2015-11-25
ZHEJIANG UNIV
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  • Abstract
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Problems solved by technology

If the amplitude of the light in the two arms of the Mach-Zehnder interferometer is not equal, it will result in poor interference

Method used

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  • Dual-ring resonant cavity-based Mach-Zehnder interferometer optical biosensor

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Embodiment

[0021] Such as figure 1 As shown, the present invention is based on a Mach-Zehnder interferometer optical biosensor assisted by a double-ring resonator, including a laser light source 1, a Mach-Zehnder interferometer 2, a first ring resonator 3, a second ring resonator 4, The first detector 5 and the second detector 6; the input end 21 of the input coupler 22 of the Mach-Zehnder interferometer 2 is connected with the laser light source 1, and the two output ends of the input coupler 22 are respectively connected with the One end of the upper arm 23 of the Mach-Zehnder interferometer 2 is connected with an end of the lower arm 24; The resonant cavity 4 is coupled; the other end of the upper arm 23 of the Mach-Zehnder interferometer 2 and the other end of the lower arm 24 are respectively connected to the two input ends of the output coupler 25; the second end of the output coupler 25 An output terminal 26 and a second output terminal 27 are respectively connected to the first ...

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Abstract

The invention discloses a dual-ring resonant cavity-based Mach-Zehnder interferometer optical biosensor, comprising a laser light source, a Mach-Zehnder interferometer, two ring-shaped waveguide resonant cavities and two detectors; the surface of a core layer of the first ring-shaped waveguide resonant cavity is modified with a biological antibody with a specific adsorption function; the surface of a core layer of the first ring-shaped waveguide resonant cavity is modified with a competition antigen for adsorbing the biological antibody; after a to be detected antigen in to be detected liquid is combined with the biological antibody, the effective refractive index of the first ring-shaped waveguide resonant cavity is caused to be increased, while the effective refractive index of the second ring-shaped waveguide resonant cavity is reduced, so that phase difference of inside light in the two ring-shaped waveguide resonant cavities is increased, the change of the phase difference is converted into the change of output power through the Mach-Zehnder interferometer, and the content of the to be detected antigen in the to be detected liquid is obtained by measuring the ratio of output powers of two ports of the Mach-Zehnder interferometer, thus greatly reducing the requirement on light source power stability.

Description

technical field [0001] The invention relates to an optical biosensor, in particular to an optical biosensor based on a double-ring resonator-assisted Mach-Zehnder interferometer. Background technique [0002] Optical biosensors have achieved rapid development due to their wide applications in biomedical diagnosis, drug discovery, environmental monitoring, and food safety. Among them, biosensors based on optical technology have many advantages: ultra-high sensitivity, strong anti-electromagnetic interference ability, high reliability, high integration and multi-parameters, so they have gained widespread attention. [0003] The dual-ring resonator-assisted Mach-Zehnder interferometer optical biosensor only needs to measure intensity information, and does not require high-resolution spectrometers or tunable lasers to measure spectral information, which greatly reduces the cost of the sensor while improving sensor sensitivity. When the frequency of the incident light is near th...

Claims

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Application Information

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IPC IPC(8): G01N21/45
Inventor 李明宇刘勇岳永恒陈阳晴唐龙华何建军
Owner ZHEJIANG UNIV
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