Extracting method and application of plant composite containing pleurotus nebrodensis

An extraction method, Bailing mushroom technology, applied in the direction of drug combination, medical preparations containing active ingredients, plant raw materials, etc., can solve the problems of large dosage, backwardness, and many impurities for patients, and achieve the effect of reducing dosage

Inactive Publication Date: 2015-12-09
南京多宝生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] In the prior art, there is no report on the use of microwave technology in the extraction and preparation of the plant composition containing Bailing mushroom. However, the method of decocting in water is rough and backward, and there are many impurities, which leads to excessive dosage for patients and is inconvenient to take. , seriously affecting the clinical application of this product

Method used

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  • Extracting method and application of plant composite containing pleurotus nebrodensis
  • Extracting method and application of plant composite containing pleurotus nebrodensis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Take 100g of Bailing mushroom, 40g of red nan, 80g of Hemeng leaves, and 160g of white flower lantern, crush them, add 2L of 70% ethanol, and put them into a microwave extraction device for microwave extraction. The extraction power is 400-600W, and the extraction is performed twice. For 4-8 minutes, combine the extracts, concentrate, add to D101 macroporous adsorption resin column, elute with 50% ethanol, collect 5 times the column volume eluate, recover ethanol under reduced pressure, concentrate and dry to obtain microwave extract , add conventional excipients to prepare tablets, each tablet 0.4g.

Embodiment 2

[0016] Take 100g of Bailing mushroom, 40g of red nan, 80g of Hemeng leaves, and 160g of white flower lantern, crush them, add 2L of 70% ethanol, and put them into a microwave extraction device for microwave extraction. The extraction power is 400-600W, and the extraction is performed twice. For 4-8 minutes, combine the extracts, concentrate, add to D101 macroporous adsorption resin column, elute with 50% ethanol, collect 5 times the column volume eluate, recover ethanol under reduced pressure, concentrate and dry to obtain microwave extract , and add conventional auxiliary materials to prepare capsules.

Embodiment 3

[0018] Take 100g of Bailing mushroom, 40g of red nan, 80g of Hemeng leaves, and 160g of white flower lantern, crush them, add 2L of 70% ethanol, and put them into a microwave extraction device for microwave extraction. The extraction power is 400-600W, and the extraction is performed twice. For 4-8 minutes, combine the extracts, concentrate, add to D101 macroporous adsorption resin column, elute with 50% ethanol, collect 5 times the column volume eluate, recover ethanol under reduced pressure, concentrate and dry to obtain microwave extract , and add conventional auxiliary materials to prepare granules.

[0019] Red Nan (Syzygiumbuxifolium Hook. et Arn.) is a shrub or small tree plant of the family Myrtleaceae. Heat-clearing and toxic substances removing, inducing diuresis and relieving asthma. Root, root bark: edema, asthma; external use for burns and scalds. Leaves: used for whitlows, furuncles, lacquer sores, burns and scalds. The present invention is used as medicine wi...

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Abstract

The invention provides an extracting method of a plant composite containing pleurotus nebrodensis. The plant composite is prepared from the raw material herbs of 100 g of pleurotus nebrodensis, 40 g of syzygium buxifolium, 80 g of sensitive joint vetch leaves and 160 g of clerodendrum fortunatum. The plant composite is prepared by the adoption of the microwave extracting method, in this way, the content is greatly increased, and the usage amount is reduced. The invention further provides an application of the plant composite containing the pleurotus nebrodensis in preparation of medicine for restraining human fibrosarcoma HT-1080 cell proliferation.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine preparations, in particular to an extraction method and application of a plant composition containing Bailing mushroom. Background technique [0002] The plant composition containing Bailing mushroom is made of 100g of Bailing mushroom, 40g of red nan, 80g of Hemeng leaf, and 160g of Baihua lantern. The current extraction method is to add water and decoct twice, each time for 2-3 hours, Combine the decoctions, filter, condense into a thick paste, granulate, dry, press into 1000 tablets, and coat with sugar, that is, it can improve immunity. [0003] In the prior art, there is no report on the use of microwave technology in the extraction and preparation of the plant composition containing Bailing mushroom. However, the method of decocting in water is rough and backward, and there are many impurities, which leads to excessive dosage for patients and is inconvenient to take. , ...

Claims

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Application Information

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IPC IPC(8): A61K36/85A61P35/00
Inventor 李洋
Owner 南京多宝生物科技有限公司
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