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Drug composition for preventing and treating schizophrenia and preparing method thereof

A technology of schizophrenia and composition, which is applied in the direction of drug combination, medical preparations containing active ingredients, and pharmaceutical formulas, and can solve problems such as lack of research literature, scattered medication, and difficulty in syndrome differentiation in traditional Chinese medicine

Inactive Publication Date: 2016-05-25
JINAN XINGYI MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are still some problems in the research of traditional Chinese medicine in the treatment of schizophrenia: (1) The effect of traditional Chinese medicine in the treatment of schizophrenia is slow, and some patients in the acute stage have difficulty in taking medicine; , compared with western medicine, it is difficult to promote and popularize traditional Chinese medicine in the treatment of schizophrenia; (3) the current clinical reports are mostly limited to the observation of clinical efficacy, and there is a lack of research literature on related mechanisms

Method used

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  • Drug composition for preventing and treating schizophrenia and preparing method thereof

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Comparison scheme
Effect test

Embodiment 1

[0038] Embodiment 1: the pharmaceutical composition for preventing and treating schizophrenia and its preparation method

[0039] The composition and parts by weight of the raw materials of the pharmaceutical composition for preventing and treating schizophrenia are: 970g of the herb Triangle Maple, 125g of the hollyhock seeds, 2020g of the wolfberry, 77g of the iso-anise coumarin, 77g of saikosaponin C, 7g of 44g of liquiritigenin;

[0040] Preparation:

[0041] (1) According to the ratio of raw materials, take marshmallow seeds, sycamore, herbaceous triangular maple, isoanisel coumarin, saikosaponin C, and liquiritigenin C, mix them evenly, and use ethanol with a concentration of 22.5% by weight as a solvent , at 23.5°C for warm immersion extraction, the number of extractions is 6 times, each extraction time is 27 hours, and the amount of solvent used each time is 23.5 times the total weight of the raw material drug, and filtered to obtain medicinal residue A and extract A, ...

Embodiment 2

[0044] Embodiment 2: the pharmaceutical composition for preventing and treating schizophrenia and its preparation method

[0045] The composition and parts by weight of the raw materials of the pharmaceutical composition for preventing and treating schizophrenia are: 950g of the herbal triangular maple, 130g of marshmallow seeds, 2,010g of isofennel coumarin, 84g of saikosaponin C106g, and 48g of liquiritigenin;

[0046] Preparation:

[0047] (1) According to the ratio of raw materials, take marshmallow seeds, sycamore, herbaceous triangular maple, isoanisel coumarin, saikosaponin C, and liquiritigenin C, mix them evenly, and use ethanol with a concentration of 22.5% by weight as a solvent , at 23.5°C for warm immersion extraction, the number of extractions is 6 times, each extraction time is 27 hours, and the amount of solvent used each time is 23.5 times the total weight of the raw material drug, and filtered to obtain medicinal residue A and extract A, extract A Recover et...

Embodiment 3

[0050] Embodiment 3: the pharmaceutical composition for preventing and treating schizophrenia and its preparation method

[0051] The composition and parts by weight of the raw materials of the pharmaceutical composition for preventing and treating schizophrenia are: 990g of the herb Triangle maple, 120g of the marshmallow seed, 2030g of iso-anise coumarin, 70g of saikosaponin C, 8g of 40g of lilycyrrhizin C;

[0052] Preparation:

[0053] (1) According to the ratio of raw materials, take marshmallow seeds, sycamore, herbaceous triangular maple, isoanisel coumarin, saikosaponin C, and liquiritigenin C, mix them evenly, and use ethanol with a concentration of 22.5% by weight as a solvent , at 23.5°C for warm immersion extraction, the number of extractions is 6 times, each extraction time is 27 hours, and the amount of solvent used each time is 23.5 times the total weight of the raw material drug, and filtered to obtain medicinal residue A and extract A, extract A Recover ethan...

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Abstract

The invention discloses a drug composition for preventing and treating schizophrenia and a preparing method thereof. The drug composition is prepared by matching herba sanicula chinensis, abelmoschus manihot seeds, bidens frondosa, isopimpinellin, saikoside C and glepidotin C. The drug composition can be prepared into various dosage forms according to a conventional preparation technology, and the schizophrenia preventing and treating effect is remarkable.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a pharmaceutical composition for preventing and treating schizophrenia and a preparation method thereof. Background technique [0002] Schizophrenia belongs to the category of epilepsy and madness in Chinese medicine, and its location lies in the mental mechanism. Regulating qi and relieving stagnation, unobstructing the mind, and empathy are the main methods of treatment; the pathogenesis of mad disease is phlegm, fire, blood stasis, obstruction of the heart orifice, imbalance of yin and yang, and loss of control of form and spirit. Adjusting yin and yang and recovering divine mechanism are the fundamental methods. According to modern medicine, schizophrenia is a group of mental diseases with unknown etiology. Its clinical classification is quite detailed, and its treatment has developed rapidly, especially in controlling acute symptoms. Tende...

Claims

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Application Information

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IPC IPC(8): A61K36/28A61P25/18A61K36/23A61K36/185A61K31/7048A61K31/366A61K31/352
CPCA61K36/23A61K9/2031A61K9/2059A61K9/4866A61K31/352A61K31/366A61K31/7048A61K36/185A61K36/28A61K2236/333A61K2236/39A61K2236/55
Inventor 不公告发明人
Owner JINAN XINGYI MEDICAL TECH
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