A reflective real-time tumor imaging method and system

Abstract

The invention belongs to the field of tumor imaging, and particularly relates to a reflection type real-time tumor imaging method and system. The imaging method comprises the steps that the polarization direction of terahertz waves is adjusted, the terahertz waves are converted into circular polarization waves through a quarter-wave plate, then, tissue to be inspected is scanned, a signal reflected by the tissue is converted into vertical polarization polarized waves to be emitted into a detector for imaging. The imaging system comprises a terahertz source, a terahertz detector, a terahertz shaping unit, a polarization unit, a movable platform and a polarization conversion unit. The reflection type real-time tumor imaging method and system can be used as the means for real-time imaging during surgery, have advantages compared with MRI, fluorescence and the like during surgery and also have advantages compared with the B-ultrasonic technology; for the intracellular biological macromolecular detection capability, the potential for distinguishing tumor tissue common pathology patterns from molecular pathological patterns, and deeper and more abundant information is provided compared with cytology characteristics; according to the existing in-vitro brain tumor tissue research result, the clinic application probability is supported, and compared with raman spectrum, the practical stage can be entered more rapidly.

Description

technical field [0001] The invention belongs to the field of tumor imaging, and in particular relates to a reflective real-time tumor imaging method and system. Background technique [0002] Glioma is a tumor originating from glial cells, which is extremely malignant, and its 5-year mortality rate is second only to pancreatic cancer and lung cancer among systemic tumors, ranking third. The color and texture of glioma and the surrounding normal brain tissue are not obvious, so it is very difficult to identify the tumor boundary under the naked eye, and it is difficult to grasp the resection boundary during surgery. [0003] In the field of glioma treatment, there is an urgent need for a real-time imaging technology to distinguish tumor boundaries, and terahertz bioimaging features provide a technical prospect for solving this demand. [0004] In conventional techniques, such as intraoperative MRI, fluorescence and other techniques cannot be fast and real-time imaging; B-ultr...

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Problems solved by technology

[0006] In order to solve the problem that the conventional imaging technology is difficult to identify the tumor boundary under the naked eye, and it is difficult to grasp the resection boundary during the operation, the present invention proposes a reflective real-time tumor imaging method and system, which avoids tumor sampling biopsy and sectioning, and can be used as an intraoperative New approach to imaging tumors in vivo in real time

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