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A kind of pharmaceutical composition containing pronase and its preparation method

A technology of pronase and composition, applied in the field of pharmaceutical preparations, can solve the problems of unfavorable patients' medication, troublesome usage and the like

Active Publication Date: 2021-07-30
BEIJING TIDE PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The currently commercially available pronase is granules, and it is necessary to add 20,000 units of pronase (1 bag) and 1 gram of sodium bicarbonate to 50-80ml of drinking water (20-40°C) 15-30 minutes before gastroscopy. ), after shaking and dissolving, take it orally, this usage is troublesome, and it is not conducive to patients

Method used

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  • A kind of pharmaceutical composition containing pronase and its preparation method
  • A kind of pharmaceutical composition containing pronase and its preparation method
  • A kind of pharmaceutical composition containing pronase and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] prescription:

[0021]

[0022] Preparation method: put the prescription amount of pronase, sodium bicarbonate, polyethylene glycol, fumed silicon dioxide, dipotassium hydrogen phosphate, and anhydrous citric acid into a ziplock bag, mix evenly, and directly compress into tablets.

Embodiment 2

[0024] prescription:

[0025]

[0026] Preparation method: put the prescription amount of pronase, sodium bicarbonate, polyethylene glycol, micropowder silica gel, lysine, and anhydrous citric acid in a ziplock bag, mix evenly, and directly compress into tablets.

Embodiment 3

[0028] prescription:

[0029]

[0030] Preparation method: Put the prescription amount of pronase, sodium bicarbonate, sodium lauryl sulfate, fumed silicon dioxide, dipotassium hydrogen phosphate, and citric acid in a ziplock bag, mix evenly, and directly compress into tablets.

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PUM

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Abstract

The invention discloses a new dosage form of a pharmaceutical composition containing pronase. The composition contains both pronase and sodium bicarbonate as active ingredients, and can be directly used by patients. Compared with existing drugs, it is easier for patients to take medicine It is convenient and safe, and avoids adverse phenomena such as poor efficacy of the drug caused by the mismatch between the dosage of pronase and sodium bicarbonate in the process of using the drug by the patient himself.

Description

technical field [0001] The invention belongs to the field of pharmaceutical preparations, in particular to a pharmaceutical composition containing pronase and a preparation method thereof. The composition is used for gastroscopy. Background technique [0002] Gastroscopy is an important method for diagnosing upper gastrointestinal diseases. Since the stomach contains mucus, and patients have saliva and saliva during gastroscopy, the endoscope is easily interfered by the foamy mucus in the esophagus and stomach during the examination, reducing the field of vision. The clarity is not conducive to the detection of tiny lesions. Thereby increasing the rate of missed and misdiagnosed diseases and prolonging the inspection time. Masaichi Maruyama summed up the diagnosis experience of early gastric cancer in Japan and found that more than 50% of early gastric cancer had no clinical symptoms and were mainly diagnosed by gastroscopy. Among them, the meticulous degree of gastroscopi...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K49/00A61K47/02A61K47/12A61K9/20
CPCA61K9/2009A61K9/2013A61K9/2095A61K49/00
Inventor 卢迪高莹吴昀赵焰平周丽莹刘亚男
Owner BEIJING TIDE PHARMA
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