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Cross die for batch production of round biological membranes

A biomembrane and cross-shaped technology, applied in medical science, surgery, etc., can solve the problems of biocomposite membrane degradation speed and time performance indicators that cannot meet clinical needs, cannot be effectively fitted, and the fracture area is small

Inactive Publication Date: 2018-03-23
锡山区东港晓鸣电子产品经营部
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] 1. The biocomposite membrane has a relatively large volume area and a small fracture area, and 2 cannot be effectively fitted and fixed together
[0005] 2. The limitations of the current biocomposite membrane materials and manufacturing process lead to performance indicators such as the degradation rate of the biocomposite membrane and the time for the carried growth factors to release the effective drug concentration (the duration of the effective concentration is the key to the healing quality of the fracture line) Unable to meet clinical needs

Method used

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  • Cross die for batch production of round biological membranes

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Embodiment Construction

[0030] refer to figure 1 1. A cross-shaped mold for batch production of circular biofilms, comprising the following steps:

[0031] 1) Manufacture a wax model 1 whose cross-section is cross-shaped, the four corners are elliptical, and the corners coincide with the cross-section of the fracture line.

[0032] 2) Immerse the model in the first solution layer and the second solution layer in turn. The first solution forms an elastic layer, which is a dense degradable or non-degradable biofilm. The second solution layer forms a drug layer, and the material of the drug layer is human bone Biocompatible degradable or non-degradable, absorbent or non-absorbable or porous porous substances, and drugs that can promote bone healing are also encapsulated inside the drug layer;

[0033] 3) After the biological microstructure membrane is air-dried and the shape is fixed, cut the prepared biological microstructure membrane along the circumference of the ellipse of the model section accordi...

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Abstract

The invention provides a cross-shaped mold for mass production of circular biofilms, which includes a wax model with a cross-section, four elliptical corners, and the top corners coincide with the cross-section of the fracture line.

Description

technical field [0001] The invention relates to a cross-shaped mold for batch production of circular biofilms. Background technique [0002] At present, it is a frontier field of medical research to use a biocomposite film containing growth factors / stem cells to stick to the fracture line to enhance the speed and quality of fracture healing. There are blood vessels and bone cells distributed on the inner surface of the fracture line (anastomosis line), and whether the healing is good depends on the growth of blood vessels and bone cells in the fracture line. The reason why biofilm sticking to the surface of fracture anastomosis can increase the quality of fracture healing is that on the one hand, the drugs encapsulated in the biofilm can promote the growth of blood vessels and bone cells in the fracture anastomosis, and on the other hand, the biological The membrane isolates external muscles and other human tissues from the fracture anastomotic line, and prevents the reacti...

Claims

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Application Information

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IPC IPC(8): A61L31/12A61L31/06A61L31/04A61L31/02A61L31/00A61L31/14A61L31/16
CPCA61L31/06A61L31/005A61L31/024A61L31/04A61L31/042A61L31/044A61L31/046A61L31/14A61L31/146A61L31/148A61L31/16A61L2300/108A61L2300/232A61L2300/252A61L2300/30A61L2300/412A61L2300/414A61L2300/602A61L2300/604C08L67/04C08L1/02
Inventor 王玉英
Owner 锡山区东港晓鸣电子产品经营部
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