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Use of microbacterium strains for the production of antibacterial agents

A technology of Microbacterium and Microbacterium dendriticum, applied in the field of producing compounds with antibacterial activity

Inactive Publication Date: 2018-05-11
DEINOBIOTICS
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  • Summary
  • Abstract
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  • Claims
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Problems solved by technology

Among the isolated strains, Microbacterium strain MA3-7G was shown to exhibit antifungal activity, but no activity was observed against pathogenic bacteria

Method used

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  • Use of microbacterium strains for the production of antibacterial agents

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Embodiment

[0045] Hereinafter, the present invention will be specifically described by way of examples, but the present invention is not limited to these examples.

[0046] A) Qualitative evaluation of activity in liquid and solid phases

[0047] The activity of different strains of Microbacterium genus against S. aureus ATCC 13709 has been qualitatively evaluated in solid and liquid phase (Table 1). Strains 1 to 8 belonged to the species Microbacterium dendriticum and strains 9 to 19 belonged to different species of the genus Microbacterium, but said species could not be identified.

[0048] Table 1

[0049] strain

[0050] It has now been found that activity is observed depending on the nature of the phase in which the Microbacterium strain is cultured.

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Abstract

The present invention relates to the use of a bacterium of the genus Microbacterium for the production of a compound endowed with antibacterial activity.

Description

Background technique [0001] Antimicrobial resistance, the ability of microorganisms to find ways to circumvent the effects of drugs used to treat infections caused by such microorganisms, is considered a current public health problem not only because of the Bacteria are growing trend, but also due to lack of new antibiotics. [0002] Consequently, there is a growing demand for antibiotics not only because of resistance issues but also due to increasing life expectancy in the population. [0003] For example, multidrug-resistant Gram-positive bacteria (MDRGP), which continues to challenge the scientific community, involves Staphylococcus aureus, the first penicillin-resistant strain of which emerged in 50 years ago. In addition, multidrug-resistant Gram-negative bacteria (MDRGN) have also become a concern, especially drug-resistant strains of Escherichia coli (E. coli). [0004] It has never been demonstrated in the literature that strains belonging to the genus Microbacteri...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12P1/04C12R1/00A01N63/02A01N63/20
CPCC12P1/04A01N63/20C12N1/20C12R2001/01
Inventor 帕斯卡尔·迪尔斯泰尔多米尼克·勒拜莱尔简保罗·莱奥内蒂于格·曼达维答普蕾玛维西·勒瓦瑟玛乔丽·瓦伦杜克
Owner DEINOBIOTICS
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