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Povidone iodine hydrogel antibacterial dressing and preparation method thereof

A technology of povidone iodine and hydrogel, which is applied in the field of medicine, can solve problems such as unsatisfactory treatment effects, and achieve the effects of preventing infection, enhancing antibacterial properties, and accelerating wound healing

Inactive Publication Date: 2018-06-22
GUANGZHOU RAINHOME PHARM&TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the existing methods and products are often unsatisfactory in terms of therapeutic effect

Method used

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  • Povidone iodine hydrogel antibacterial dressing and preparation method thereof
  • Povidone iodine hydrogel antibacterial dressing and preparation method thereof
  • Povidone iodine hydrogel antibacterial dressing and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] A povidone-iodine hydrogel antibacterial dressing, said povidone-iodine hydrogel antibacterial dressing is made from the following raw materials in parts by weight: 0.25 part of chitosan, 0.5 part of povidone-iodine, 0.5 part of propylene glycol , 2 parts of glycerin, 10 parts of poloxamer, 2 parts of acetic acid, 100 parts of purified water. The degree of deacetylation of the chitosan is 91%, and the molecular weight of the chitosan is 4000. The povidone-iodine is a complex compound of iodine and polyvinylpyrrolidone, and the effective content of iodine is 9%.

[0028] A preparation method of povidone-iodine hydrogel antibacterial dressing, comprising the following steps:

[0029] 1) Add the acetic acid of formula quantity to the purified water of formula quantity, stir until completely dissolved;

[0030] 2) Take an appropriate amount of the acetic acid aqueous solution prepared in step 1), add the formulated amount of poloxamer while stirring, stir evenly, and let ...

Embodiment 2

[0035] A povidone-iodine hydrogel antibacterial dressing, said povidone-iodine hydrogel antibacterial dressing is made from the following raw materials in parts by weight: 1 part of chitosan, 3 parts of povidone-iodine, 2 parts of propylene glycol , 6 parts of glycerin, 20 parts of poloxamer, 4 parts of acetic acid, 120 parts of purified water. The degree of deacetylation of the chitosan is 99%, and the molecular weight of the chitosan is 10000. The povidone-iodine is a complex compound of iodine and polyvinylpyrrolidone, and the effective content of iodine is 12%.

[0036] A preparation method of povidone-iodine hydrogel antibacterial dressing, comprising the following steps:

[0037] 1) Add the acetic acid of formula quantity to the purified water of formula quantity, stir until completely dissolved;

[0038] 2) Take an appropriate amount of the acetic acid aqueous solution prepared in step 1), add the formulated amount of poloxamer while stirring, stir evenly and let it s...

Embodiment 3

[0043] A povidone-iodine hydrogel antibacterial dressing, said povidone-iodine hydrogel antibacterial dressing is made from the following raw materials in parts by weight: 0.5 part of chitosan, 1 part of povidone-iodine, 1 part of propylene glycol , 3 parts of glycerin, 13 parts of poloxamer, 2.5 parts of acetic acid, 105 parts of purified water. The degree of deacetylation of the chitosan is 93%, and the molecular weight of the chitosan is 6000. The povidone-iodine is a complex compound of iodine and polyvinylpyrrolidone, and the effective content of iodine is 10%.

[0044] A preparation method of povidone-iodine hydrogel antibacterial dressing, comprising the following steps:

[0045] 1) Add the acetic acid of formula quantity to the purified water of formula quantity, stir until completely dissolved;

[0046] 2) Take an appropriate amount of the acetic acid aqueous solution prepared in step 1), add the formulated amount of poloxamer while stirring, stir evenly and let it ...

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Abstract

The invention relates to a povidone iodine hydrogel antibacterial dressing and a preparation method thereof, and belongs to the field of medicines. In view of deficiencies of the prior art, a purposeof the invention is to provide a povidone iodine hydrogel antibacterial dressing prepared from the following raw materials in parts by weight: 0.25 to 1 part of chitosan, 0. 5 to 3 parts of povidone iodine, 0.5 to 2 parts of propylene glycol, 2 to 6 parts of glycerin, 10 to 20 parts of poloxamer, 2 to 4 parts of acetic acid, and 100 to 120 parts of purified water. The antibacterial dressing can not only make the wound in a humid environment, but also relieves the release of a pharmaceutical effect of the povidone iodine, prolongs the duration of the pharmaceutical effect, has a good antibacterial effect, stability, and a wide application range, has a good therapeutic effect on healing of the wound, promotes skin regeneration, and reduces scar formation.

Description

technical field [0001] The invention relates to a povidone-iodine hydrogel antibacterial dressing and a preparation method thereof, belonging to the field of medicine. Background technique [0002] Polyvinylpyrrolidone-iodine (PVP-I2, commonly known as povidone-iodine, pevi-iodine) is a topical disinfectant and preservative, which is an amorphous compound formed by the complexation of polymer polyvinylpyrrolidone and iodine. The solution depolymerizes and releases iodine after contacting the affected area such as the disinfected surface or wound, so as to achieve the effect of antibacterial and anti-inflammatory. Povidone-iodine has broad-spectrum and high-efficiency bactericidal characteristics, and has become a widely used high-efficiency bactericidal disinfectant. [0003] The disinfection quality of povidone-iodine depends on the stability of the available iodine content. Although it overcomes the shortcomings of low iodine solubility, instability, and prone to allergic...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L26/00
CPCA61L26/0014A61L26/0023A61L26/0066A61L26/008A61L2300/106A61L2300/236A61L2300/404A61L2300/45A61L2300/602C08L5/08C08L39/06
Inventor 张聪车七石
Owner GUANGZHOU RAINHOME PHARM&TECH CO LTD
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