Reagent test strips comprising reference regions for measurement with colorimetric test platform

A test area and test strip technology, used in the field of manufacturing reagent test strips, reagent test strips, and measuring the concentration of analytes, which can solve the problems of small change systems that cannot distinguish colors, a large amount of processing capacity, and hindering quantitative color measurement.

Inactive Publication Date: 2019-02-05
SPARK DIAGNOSTICS LLC
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the use of colorimetric image analysis for such diagnostic assays using images captured from mobile phone cameras still has many limitations, such as (a) the influence of changing lighting conditions during image acquisition; (b) due to the integration at the pixel level The automatic color balancing of various mobile phone operating systems prevents accurate quantitative color measurement and also requires image correction; (c) performing image analysis requires a lot of processing power; and (d) the colors cannot be distinguished by typical color measurements small change system

Method used

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  • Reagent test strips comprising reference regions for measurement with colorimetric test platform
  • Reagent test strips comprising reference regions for measurement with colorimetric test platform
  • Reagent test strips comprising reference regions for measurement with colorimetric test platform

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Embodiment Construction

[0062] The invention is best understood by reference to the detailed description set forth herein and the accompanying drawings. Various embodiments are discussed below with reference to the figures. Those skilled in the art will readily appreciate, however, that the detailed description given herein with respect to the figures is for explanatory purposes only, as the methods and systems may extend beyond the described embodiments. For example, the teachings given and the requirements of a particular application may dictate many alternative and suitable ways of implementing the functionality of any detail described herein. Accordingly, any method may extend beyond the specific implementation options described and illustrated in the following examples.

[0063] References to "an embodiment", "at least one embodiment", "an embodiment", "an example", "example", "for example", etc. indicate that an embodiment or an example) may include particular features, structures, characteris...

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Abstract

Disclosed is a reagent strip comprising test region(s) and reference region(s). The reference region(s) display a predetermined response to possible concentrations of an analyte applied to the corresponding test region(s). Furthermore, the reference region(s) and the test region(s) are arranged on the reagent strip to facilitate analysis of a qualitative state of the analyte and optionally, calculation of a quantitative value of the analyte at point-of-collection. Also disclosed is a method of manufacturing such reagent strips, and the method includes printing the reference region(s) and the test region(s) in a continuous and alternating series on a test strip precursor substrate. The method also involves cutting the test strip precursor substrate perpendicularly to the printed columns toobtain reagent strips. Also disclosed is a method encompassed in a mobile application for determining a qualitative state and optionally calculating a quantitative state of the analyte.

Description

technical field [0001] The present invention relates to the field, and in particular, to a reagent test strip, a method of manufacturing a reagent test strip, and a method of measuring an analyte concentration using a reagent test strip, the reagent test strip including one or more reference areas to facilitate the analysis of the The qualitative state of the analyte, and determine the quantitative value of the analyte through a data processing device. Background technique [0002] Traditional portable colorimetric diagnostic tools that use color changes to measure analyte values ​​(eg, paper strips, microfluidic paper assays, and reagent test strip-based systems) have been available in the market for many years. This colorimetric strip is commonly used for the analysis of urine, blood, water, pH, industrial pollutants, or chemicals and has great potential to provide a simple, low-cost, fast point-of-collection (POC) system. [0003] An exemplary colorimetric reaction test ...

Claims

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Application Information

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Patent Type & AuthorityApplications(China)
IPC IPC(8): C12M1/00C12Q1/00G01N33/53G01N33/48
CPCG01N21/8483G01N2021/8488G01N33/1853G01N33/487G01N33/521G01N33/182G01N21/78G01N2021/7759G01N21/80
Inventor普里特斯·阿尔琼布海·帕特尔
OwnerSPARK DIAGNOSTICS LLC