Application of lobaplatin in preparation of medicine for treating bladder cancer
A bladder cancer and drug technology, applied in the application field of platinum drugs in bladder cancer, can solve problems such as strong side effects, and achieve the effect of significant therapeutic effect and strong anti-bladder cell tumor effect.
Pending Publication Date: 2020-04-17
吉林大学中日联谊医院
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Studies have shown that adjuvant chemotherapy can delay recurrence and improve overall survival. Neoadjuvant chemotherapy can increase the median survival rate and reduce the incidence of residual disease. In the chemotherapy of bladder cancer, the combination of chemotherapy drugs based on cisplatin is the most effective. Common chemotherapy regimens, among which
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Abstract
The invention discloses application of lobaplatin in preparation of a medicine for treating bladder cancer, belongs to the technical field of new applications of chemical medicines, and particularly relates to application of a platinum medicine in bladder cancer. The lobaplatin dosage form is a freeze-dried powder injection, a small-volume injection or a large-volume injection, and the effective treatment amount is 45-55 mg/m<2> body surface area. The lobaplatin and the lobaplatin preparation have the advantages of strong bladder cell tumor resistance, substantial treatment effect, low toxicity, safety, provision of a new treatment medicine for bladder cancer, and expansion of the clinical application of lobaplatin and the lobaplatin preparation.
Description
technical field [0001] The invention belongs to the technical field of new application of chemical drugs, and in particular relates to the application of a platinum drug in bladder cancer. Background technique [0002] Bladder cancer is the tenth most common cancer worldwide and one of the most common cancers in the urinary system. Men have a higher incidence of bladder cancer than women, and bladder cancer is the sixth most common cancer and the ninth most deadly cancer in men. Over the past 30 years, very little progress has been made in the treatment of bladder cancer, nor has its survival rate improved. Chemotherapy is an important link in the treatment of bladder cancer. Studies have shown that adjuvant chemotherapy can delay recurrence and improve overall survival. Neoadjuvant chemotherapy can increase the median survival rate and reduce the incidence of residual disease. In the chemotherapy of bladder cancer, the combination of chemotherapy drugs based on cisplatin ...
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IPC IPC(8): A61K31/282A61P35/00
CPCA61K9/0019A61K31/282A61P35/00
Inventor 于倩关丽英王颖崔海珍马志娜蓝天伟
Owner 吉林大学中日联谊医院
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