5-hydroxy-1, 7-diphenyl-3-heptanone separated from galangal and application thereof

A technology of diphenyl and galangal, applied in the separation/purification of carbonyl compounds, active ingredients of ketones, metabolic diseases, etc., can solve problems such as deficiency, improve glucose tolerance, improve IR effect, and reduce random blood sugar levels Effect
CN112645808AInactive Publication Date: 2021-04-13HAINAN MEDICAL COLLEGE
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Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Applications(China)
Current Assignee / Owner
HAINAN MEDICAL COLLEGE
Publication Date
2021-04-13
Estimated Expiration
Not applicable Β· inactive patent

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Abstract

The invention discloses 5-hydroxy-1, 7-diphenyl-3-heptanone separated from galangal and application of the 5-hydroxy-1, 7-diphenyl-3-heptanone. After the 5-hydroxy-1, 7-diphenyl-3-heptanone is intervened, sugar tolerance is obviously improved, and the effect of the 5-hydroxy-1, 7-diphenyl-3-heptanone on improving IR is obvious. The compound can up-regulate the transcriptional level of Nrf2 mRNA and downstream target genes.
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Description

technical field

[0001] The invention relates to the technical field of natural medicines, in particular to 5-hydroxyl-1,7-diphenyl-3-heptanone isolated from galangal and an application thereof. Background technique

[0002] Galangal is the dry rhizome of Alpinia officinarum Hance, a plant of the ginger family Zingiberaceae. It has the effects of warming the middle and dispelling cold, warming and relieving pain, harmonizing the stomach, and promoting qi and guiding stagnation. It is often used clinically to treat abdominal cold pain , stomach cold, vomiting and other symptoms. Chemical studies have shown that galangal mainly contains flavonoids, volatile oils and diphenylheptane compounds. Pharmacological studies have found that it has various pharmacological effects such as anti-diabetes, anti-ulcer, anti-emetic, and anti-inflammatory. It has been reported that galangal extract has a significant hypoglycemic effect. Domestic studies have also reported that galangal extra...

Claims

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