Chinese medicine preparation for treating bone fracture and preparing method thereof

A technology of traditional Chinese medicine preparations and diseases, applied in bone diseases, medical formulas, medical preparations containing active ingredients, etc., can solve the problems of slow effect, unsatisfactory treatment effect, long treatment course, etc.

Inactive Publication Date: 2005-10-12
张海峰
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Although there are traditional Chinese medicine preparations including internal and external use for the treatment of avascular necrosis of the femoral head, they all have the characteristics of long treatment period and slow effect, and the therapeutic effect is not very satisfactory.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] (1) The raw materials are: Rhizoma drynariae 4000g, sarcocarpus 4000g, pigeon pea leaf 4000g.

[0042] (2) Take the above-mentioned Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizome, and pigeonpea leaf medicinal materials, pulverize, add 15 times the amount of water to soak for 2 hours, extract the volatile oil by steam distillation for 5 hours, collect the volatile oil, water extract and medicinal residue for subsequent use; After dissolving the volatile oil with ethanol, add 40 times the amount of volatile oil to a saturated solution made of HP-β-CD, stir at 50°C for 3 hours, then stir at room temperature for another 2 hours, let stand overnight, filter, and dry at low temperature to obtain 3200g of clathrate .

[0043](3) Extract the above-mentioned dregs with 6 times the amount of 30% ethanol solution once again, combine the two extracts, filter, and concentrate the filtrate under reduced pressure to form an extract, add 30 times the amount of ...

Embodiment 2

[0046] (1) The raw materials are: drynaria rhizome 3000g, sarcophagus 3000g, pigeon pea leaf 3000g.

[0047] (2) Take the above-mentioned Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizome, and pigeonpea leaf medicinal materials, pulverize, add 8 times the amount of water to soak for 2 hours, extract the volatile oil by steam distillation for 3 hours, collect the volatile oil, water extract and medicinal residue for subsequent use; After dissolving the volatile oil with ethanol, add 20 times the amount of volatile oil to a saturated solution made of HP-β-CD, stir at 50°C for 3 hours, then stir at room temperature for another 2 hours, let stand overnight, filter, and dry at low temperature to obtain 1500g of clathrate .

[0048] (3) Extract the above-mentioned dregs with 12 times the amount of 70% ethanol solution once again, combine the two extracts, filter, and concentrate the filtrate under reduced pressure to form an extract, add 20 times the amount of ...

Embodiment 3

[0051] (1) The raw materials are: Rhizoma drynariae 3500g, sarcophagus 3500g, pigeonpea leaf 3500g.

[0052] (2) Take the above-mentioned drynaria rhizome, rhizoma rhizomes, and pigeonpea leaves, pulverize them, add 10 times the amount of water to soak for 2 hours, extract the volatile oil by steam distillation for 4 hours, collect the volatile oil, water extract and medicinal residue for subsequent use; After dissolving the volatile oil with ethanol, add 30 times the amount of volatile oil to a saturated solution made of HP-β-CD, stir at 50°C for 3 hours, then stir at room temperature for 2 hours, let stand overnight, filter, and dry at low temperature to obtain 2600g of clathrate .

[0053] (3) Extract the above-mentioned dregs with 10 times the amount of 60% ethanol solution once more, combine the two extracts, filter, and concentrate the filtrate under reduced pressure to form an extract, add 25 times the amount of hot water at 80°C, stir, and After filtration, the filtra...

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PUM

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Abstract

A Chinese medicine for treating bone injury and ischemic necrosis of femur head is prepared from fortune's drynaria rhizome, cajan leaf, glabrous sarcandra herb and medicinal additive. Its preparing process is also disclosed.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine pharmacy, and in particular relates to a traditional Chinese medicine preparation for treating orthopedic diseases and a preparation method thereof. Background technique [0002] Avascular necrosis of the femoral head is a stubborn and disabling common orthopedic disease. It is a "worldwide orthopedic problem" and one of the three major international orthopedic diseases. The disease is often caused by clinical long-term use of hormones, trauma and alcohol consumption. Once the onset, even if the hormone is stopped immediately, it is difficult to prevent the lesions from continuing to develop. Most patients will go through the "painful trilogy" of ischemic necrosis, collapse, and osteoarthritis. [0003] Although great progress has been made in the diagnosis of avascular necrosis of the femoral head, there has been little breakthrough in the treatment, especially drug treatme...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/08A61K9/10A61K9/16A61K9/20A61K9/48A61P19/08
Inventor 张海峰
Owner 张海峰
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