Thymosin beta4 derivative and itsuse

A technology of derivatives and peptide thymus, which is applied in the field of protein drug derivatives, can solve the problem of heart disease therapy changing the way medical staff deal with heart disease
CN1935838AActive Publication Date: 2007-03-28BEIJING NORTHLAND BIOTECH
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
BEIJING NORTHLAND BIOTECH
Publication Date
2007-03-28

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Abstract

The invention relates to one section of thymosin beta 4 derivatives with high bioactivity which can be used to repair cornea, skin, and heart injury.
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Description

1. Technical field

[0001] The present invention belongs to the field of production of protein drug derivatives. By modifying the natural protein thymosin β4 (Tβ4), a derivative of Tβ4, Gly-Tβ4, was obtained. Experiments have proved that the derivative plays a very important role in the repair process of damaged tissues, and is expected to be developed as a new drug for the benefit of human beings. 2. Background technology

[0002] The immune system is the body's defense system. The main cells involved in the immune response are T lymphocytes, B lymphocytes and macrophages. The thymus is the central immune organ for the development and differentiation of T lymphocytes. Thymus factors (or hormones) secreted by the thymus are a series of essential substances required for the development and differentiation of T lymphocytes, among which thymosin β4 (Tβ4) is a major thymus factor whose structure and function have been clarified. Thymosin-beta 4 enhanced embryonic and postnata...

Claims

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