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Preparation for treating chronic nasosinusitis, preparation method and quality control method

A technology for chronic rhinitis and sinusitis, applied in the field of traditional Chinese medicine, can solve the problems of insufficient dosage forms, inconvenient taking of capsules, and high bioavailability

Inactive Publication Date: 2007-05-09
王凌
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The object of the present invention is to: provide a kind of preparation for treating chronic rhinitis and sinusitis and its preparation method and quality control method; , the problem of insufficient dosage forms, and good disintegration and high bioavailability; the preparation method provided by the present invention can effectively prepare the required preparation and ensure that the production process of the obtained preparation is scientific and reasonable; the quality control method provided can provide Relevant production and testing institutions provide testing indicators, testing methods, technical methods, etc., in order to better control the quality of the preparation, ensure the safety of medication, better guide production, and make the production process control more strict and reasonable , so that consumers can fully understand the quality of the product

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0354] Example 1 of the present invention: Xanthium 285.7g, honeysuckle 17.9g, wild chrysanthemum 17.9g, magnolia 53.6g, madder 17.9g

[0355] Take honeysuckle, magnolia, and wild chrysanthemum, add 10 times the amount of water to decoct for 6 hours, extract the volatile oil, and collect the distilled aqueous solution in another device; add cocklebur to medicinal dregs, add 8 times the amount of water to decoct twice, 3 hours each time , combined decoction, filtered, the filtrate was combined with the above aqueous solution, the combined solution was concentrated to an appropriate amount, and ethanol was added to make the alcohol content reach 60%, stirred well, left standing, filtered, and the filtrate was used for later use; As a solvent, after soaking for 24 hours, carry out percolation at a speed of 3-5ml / min.kg, collect 12 times the amount of percolation liquid, combine it with the above-mentioned filtrate, recover ethanol and concentrate it under reduced pressure to 80 ° ...

Embodiment 2

[0356] Example 2 of the present invention: Xanthium 285.7g, honeysuckle 17.9g, wild chrysanthemum 17.9g, magnolia 53.6g, madder 17.9g

[0357] Take honeysuckle, magnolia, and wild chrysanthemum, add 10 times the amount of water to decoct for 6 hours, extract the volatile oil, and collect the distilled aqueous solution in another device; add cocklebur to medicinal dregs, add 8 times the amount of water to decoct twice, 3 hours each time , combined decoction, filtered, the filtrate was combined with the above aqueous solution, the combined solution was concentrated to an appropriate amount, and ethanol was added to make the alcohol content reach 60%, stirred well, left standing, filtered, and the filtrate was used for later use; As a solvent, after soaking for 24 hours, carry out percolation at a speed of 3-5ml / min.kg, collect 12 times the amount of percolation liquid, combine it with the above-mentioned filtrate, recover ethanol and concentrate it under reduced pressure to 80 ° ...

Embodiment 3

[0358] Example 3 of the present invention: Xanthium 285.7g, honeysuckle 17.9g, wild chrysanthemum 17.9g, magnolia 53.6g, madder 17.9g

[0359] Take honeysuckle, magnolia, and wild chrysanthemum, add 10 times the amount of water to decoct for 6 hours, extract the volatile oil, and collect the distilled aqueous solution in another device; add cocklebur to medicinal dregs, add 8 times the amount of water to decoct twice, 3 hours each time , combined decoction, filtered, the filtrate was combined with the above aqueous solution, the combined solution was concentrated to an appropriate amount, and ethanol was added to make the alcohol content reach 60%, stirred well, left standing, filtered, and the filtrate was used for later use; As a solvent, after soaking for 24 hours, carry out percolation at a speed of 3-5ml / min.kg, collect 12 times the amount of percolation liquid, combine it with the above-mentioned filtrate, recover ethanol and concentrate it under reduced pressure to 80 ° ...

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PUM

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Abstract

A Chinese medicine in the form of dripping pill, dispersing tablet, or micropill for treating chronic rhinitis and nasosinusitis is prepared from xanthium fruit, honeysuckle flower, wild chrysanthemum flower, magnolia flower and madder. Its preparing process and quality control method are also disclosed.

Description

technical field [0001] The invention relates to a preparation for treating chronic rhinitis and sinusitis, a preparation method and a quality control method thereof, and belongs to the technical field of traditional Chinese medicines. Background technique [0002] Nasal congestion is the most common symptom of chronic rhinitis and chronic sinusitis. Due to the stuffy nose, the patient can only open his mouth to breathe. After a long time, the mouth becomes dry, dizzy, in a trance, unable to fall asleep all night, and thus induces many diseases such as chronic pharyngitis, and the harm is very serious. Although nasal congestion is a common symptom, it recurs and persists, making it difficult for doctors and painful for patients. Traditional Chinese medicine has a systematic understanding of chronic rhinitis and chronic sinusitis. Traditional Chinese medicine has the advantages of good curative effect, small side effects and low cost in treating such diseases. Biyuan Capsule...

Claims

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Application Information

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IPC IPC(8): A61K36/74A61K9/00A61K9/06A61K9/08A61K9/10A61K9/14A61K9/16A61K9/19A61K9/20A61K9/48A61K9/50A61P11/02G01N30/02G01N30/90
Inventor 于文风
Owner 王凌
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