Combinations of inhibin with bronchodilators
A technology of bronchodilators and statins, applied in drug combinations, antipyretics, pharmaceutical formulations, etc., can solve problems such as systemic inflammation that has not been optimized
Inactive Publication Date: 2007-06-20
ASTRAZENECA AB
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- Abstract
- Description
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- Application Information
AI Technical Summary
Problems solved by technology
[0006] In addition, anti-inflammatory drugs currently developed for the signs and symptoms of specific diseases may not be optimized for the long-term treatment of concurrent systemic inflammation, which is postulated to be the cause of many common pathologies
Method used
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Experimental program
Comparison scheme
Effect test
Embodiment 1
[0083] Example 1 - Inhalation - Dry Powder
[0084] INGREDIENTS PER DOSAGE
[0085] Formoterol (as fumarate dihydrate) 4.5 μg
[0086] Budesonide 160μg
[0087] Rosuvastatin 1mg
Embodiment 2
[0088] Example 2 - Inhalation - Metered dose inhaler
[0089] INGREDIENTS PER DOSAGE
[0090] Formoterol (as fumarate dihydrate) 4.5 μg
[0091] Budesonide 160μg
[0092] Rosuvastatin 1mg
[0093] HFA227 50μl
Embodiment 3
[0094] Example 3 - Inhalation - Dry Powder
[0095] INGREDIENTS PER DOSAGE
[0096] Formoterol (as fumarate dihydrate) 4.5 μg
[0097] Budesonide 160μg
[0098] Rosuvastatin 1mg
[0099] Lactose up to 1, 2, 5, 10 or 20mg
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The invention provides medicaments comprising combinations of bronchodilators, glucocorticosteroids and HMG-CoA reductase inhibitors in the treatment of respiratory disorders such as chronic obstructive pulmonary disease (COPD).
Description
technical field [0001] The present invention provides medicaments for the treatment of respiratory diseases such as chronic obstructive pulmonary disease (COPD) comprising combinations of bronchodilators, glucocorticosteroids and HMG-CoA reductase inhibitors. Background technique [0002] The diagnosis and treatment of many diseases focus, for obvious reasons, on the typical criteria and manifestations that are characteristic of a particular disease (thereby distinguishing it from other diseases). Examples are joint-related signs and symptoms in rheumatoid arthritis (RA), and lung function tests in COPD. [0003] But many diseases have significant co-morbidity, and they are often considered "other" diseases because they are not unique to or specific to the primary disease. For example, cardiovascular co-morbidities may often be considered indeterminate and not directly related to primary diseases such as RA or COPD. However, co-morbidities can be as important as regular ma...
Claims
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IPC IPC(8): A61K31/40A61K31/505A61K31/58A61K31/165A61P11/00A61P11/06A61P11/08
CPCA61K31/505A61K31/165A61K31/58A61K45/06A61K31/40A61P11/00A61P11/06A61P11/08A61P19/02A61P29/00A61P43/00A61K2300/00
Inventor 伯蒂尔·林德马克安德斯·I·索伦
Owner ASTRAZENECA AB
