Binary-packaged reactive chlorine dioxide tablet and preparation method thereof

Abstract

The invention discloses a binary-packaged reactive chlorine dioxide tablet which comprises an independently-packaged tablet A and an independently-packaged tablet B, wherein the tablet A is prepared into tablets from the following raw materials through mixing and pressing: 55-65wt% of native agent, 8-12wt% of dissolution agent, 8-11wt% of foaming agent, 8-11wt% of adhesion agent, 8-11wt% of forming agent, and 0.01-0.5wt% of mould release agent; and the tablet B is prepared into tablets from the following raw materials through mixing and pressing: 35-50wt% of acidating agent, 20-30wt% of catalyst, 3-8wt% of foaming agent, 10-15wt% of adhesion agent, 10-15wt% of forming agent, and 0.05-0.2wt% of mould release agent; then, the tablet A and the tablet B are respectively coated by a coating agent so as to obtain the binary-packaged reactive chlorine dioxide tablet. When the binary-packaged reactive chlorine dioxide tablet is used, chlorine dioxide gas can be generated just by adding the tablet A and the tablet B into water in certain proportion to dissolve, thereby achieving the effects of sterilization and disinfection. The binary-packaged reactive chlorine dioxide tablet disclosed bythe invention is high in conversion rate, easy to store and high in product stability.

Description

technical field

[0001] The invention belongs to the technical field of chlorine dioxide disinfection, and in particular relates to a binary reaction chlorine dioxide solid preparation composed of alkali metal or alkaline earth metal chlorite such as sodium chlorite, solid acid and other accelerators. . The invention also relates to a preparation method of the solid preparation. Background technique

[0002] As a water-soluble strong oxidant, chlorine dioxide has high-efficiency and broad-spectrum bactericidal ability, and can oxidize and decompose bacteria, viruses and other microorganisms, as well as amino acids and other reducing substances in proteins, and can also react with organic matter and various inorganic ions reaction; and, compared with other chlorine-based products, chlorine dioxide will not produce distortion-causing, carcinogenic, mutagenic chloroform and other organic halides during sterilization, and the effect of killing viruses, bacteria, deodorization, b...

Examples

Embodiment 1

[0047] 1) Grind each raw material and pass through a 100-120 mesh sieve, retain the raw material with intermediate particle size, and dry it at 40-120°C for 2 hours;

[0048] 2) Weigh 6Kg of sodium chlorite, 1Kg of citric acid, 1Kg of sodium carbonate, 1Kg of β-cyclodextrin, 0.8Kg of polyethylene glycol (molecular weight 6000), 0.02Kg of magnesium stearate, mix well, and press into Binary reactive chlorine dioxide tablet A;

[0049] 3) Weigh 4.3Kg of sulfamic acid + sodium bisulfate (mass ratio 1:2), 2.5Kg of sodium bromide, 0.6Kg of sodium bicarbonate, 1.2Kg of β-cyclodextrin, polyethylene glycol (molecular weight 6000) 1.2Kg, 0.01Kg of magnesium stearate, compressed into binary reactive chlorine dioxide tablets B;

[0050] 4) Dissolve polyethylene glycol in an ethanol solution with a concentration of 75%, prepare a sufficient volume of polyethylene glycol coating solution with a concentration of 6%, and use a coating pan for the binary reactions prepared in 2) and 3). Type...

Embodiment 2

[0053] 1) Weigh 5.5Kg of sodium chlorite, 1.1Kg of citric acid, 1Kg of sodium carbonate, 1Kg of β-cyclodextrin, 1Kg of polyethylene glycol (molecular weight 6000), 0.02Kg of magnesium stearate, mix well, and press into binary reactive chlorine dioxide tablets A;

[0054] 2) Weigh 4Kg of sulfamic acid + sodium bisulfate (mass ratio 1:2), 2.7Kg of sodium bromide, 0.7Kg of sodium bicarbonate, 1.3Kg of β-cyclodextrin, 1.2Kg of polyethylene glycol (molecular weight 6000) Kg, magnesium stearate 0.01Kg, compressed into binary reaction type chlorine dioxide tablet B;

[0055] 3) Other preparation steps are the same as in Example 1.

Embodiment 3

[0057] 1) Weigh 6.5Kg of sodium chlorite, 0.9Kg of citric acid, 0.8Kg of sodium carbonate, 0.8Kg of β-cyclodextrin, 0.8Kg of polyethylene glycol (molecular weight 6000), 0.02Kg of magnesium stearate, and mix well Afterwards, it is compressed into a binary reactive chlorine dioxide tablet A;

[0058] 2) Weigh 4.3Kg of sulfamic acid + sodium bisulfate (mass ratio 1:2), 2.4Kg of sodium bromide, 0.6Kg of sodium bicarbonate, 1.3Kg of β-cyclodextrin, polyethylene glycol (molecular weight 6000) 1.2Kg, 0.01Kg of magnesium stearate, compressed into binary reactive chlorine dioxide tablets B;

[0059] 3) Other preparation steps are the same as in Example 1.

technical field

[0001] The invention belongs to the technical field of chlorine dioxide disinfection, and in particular relates to a binary reaction chlorine dioxide solid preparation composed of alkali metal or alkaline earth metal chlorite such as sodium chlorite, solid acid and other accelerators. . The invention also relates to a preparation method of the solid preparation. Background technique

[0002] As a water-soluble strong oxidant, chlorine dioxide has high-efficiency and broad-spectrum bactericidal ability, and can oxidize and decompose bacteria, viruses and other microorganisms, as well as amino acids and other reducing substances in proteins, and can also react with organic matter and various inorganic ions reaction; and, compared with other chlorine-based products, chlorine dioxide will not produce distortion-causing, carcinogenic, mutagenic chloroform and other organic halides during sterilization, and the effect of killing viruses, bacteria, deodorization, b...

Examples

Embodiment 1

[0047] 1) Grind each raw material and pass through a 100-120 mesh sieve, retain the raw material with intermediate particle size, and dry it at 40-120°C for 2 hours;

[0048] 2) Weigh 6Kg of sodium chlorite, 1Kg of citric acid, 1Kg of sodium carbonate, 1Kg of β-cyclodextrin, 0.8Kg of polyethylene glycol (molecular weight 6000), 0.02Kg of magnesium stearate, mix well, and press into Binary reactive chlorine dioxide tablet A;

[0049] 3) Weigh 4.3Kg of sulfamic acid + sodium bisulfate (mass ratio 1:2), 2.5Kg of sodium bromide, 0.6Kg of sodium bicarbonate, 1.2Kg of β-cyclodextrin, polyethylene glycol (molecular weight 6000) 1.2Kg, 0.01Kg of magnesium stearate, compressed into binary reactive chlorine dioxide tablets B;

[0050] 4) Dissolve polyethylene glycol in an ethanol solution with a concentration of 75%, prepare a sufficient volume of polyethylene glycol coating solution with a concentration of 6%, and use a coating pan for the binary reactions prepared in 2) and 3). Type...

Embodiment 2

[0053] 1) Weigh 5.5Kg of sodium chlorite, 1.1Kg of citric acid, 1Kg of sodium carbonate, 1Kg of β-cyclodextrin, 1Kg of polyethylene glycol (molecular weight 6000), 0.02Kg of magnesium stearate, mix well, and press into binary reactive chlorine dioxide tablets A;

[0054] 2) Weigh 4Kg of sulfamic acid + sodium bisulfate (mass ratio 1:2), 2.7Kg of sodium bromide, 0.7Kg of sodium bicarbonate, 1.3Kg of β-cyclodextrin, 1.2Kg of polyethylene glycol (molecular weight 6000) Kg, magnesium stearate 0.01Kg, compressed into binary reaction type chlorine dioxide tablet B;

[0055] 3) Other preparation steps are the same as in Example 1.

Embodiment 3

[0057] 1) Weigh 6.5Kg of sodium chlorite, 0.9Kg of citric acid, 0.8Kg of sodium carbonate, 0.8Kg of β-cyclodextrin, 0.8Kg of polyethylene glycol (molecular weight 6000), 0.02Kg of magnesium stearate, and mix well Afterwards, it is compressed into a binary reactive chlorine dioxide tablet A;

[0058] 2) Weigh 4.3Kg of sulfamic acid + sodium bisulfate (mass ratio 1:2), 2.4Kg of sodium bromide, 0.6Kg of sodium bicarbonate, 1.3Kg of β-cyclodextrin, polyethylene glycol (molecular weight 6000) 1.2Kg, 0.01Kg of magnesium stearate, compressed into binary reactive chlorine dioxide tablets B;

[0059] 3) Other preparation steps are the same as in Example 1.