Maca composition for relieving climacteric symptoms of females and preparation method thereof

Abstract

The invention relates to a maca composition for relieving the climacteric symptoms of females and a preparation method thereof. The maca composition is prepared from maca extract, prepared rehmannia root extract, radix ophiopogonis extract, spina date seed extract, poria cocos extract and extract from pueraria. Natural plants are adopted as the raw materials of the maca composition, maca and traditional Chinese medicine are compounded, active ingredients are extracted in combination of the modern science and technology, the traditional Chinese medicine theory is followed in raw material composition, and on the one hand, the estrogen level in the bodies of the menopausal females is adjusted by nourishing the ovary and nourishing kidney yin; on the other hand, the sub-health status of the menopausal females is relieved by relieving pressure, tranquilizing and allaying excitement and boosting immunity, and therefore the effect of relieving the climacteric syndromes of the females is achieved. It is proved through animal experiments that the maca composition has remarkable effects on relieving the climacteric syndromes of the females.

Description

technical field

[0001] The invention belongs to the field of traditional Chinese medicine health care products, and more specifically relates to a maca prescription for relieving menopausal symptoms of women and a preparation method thereof. Background technique

[0002] Menopause, also known as perimenopause, refers to the transitional stage of a woman's life from sexual maturity to old age, generally 45-55 years old. Ovarian dysfunction and decreased estrogen secretion lead to a series of symptoms such as endocrine dysfunction and autonomic nerve dysfunction in most menopausal women, resulting in paroxysmal hot flashes, fatigue, sweating, palpitations, insomnia, osteoarthritis, etc. Physical health problems such as porosity, accompanied by mental health problems such as depression, fear, and anxiety. At the same time, bad mental state interacts with autonomic dysfunction, easily forming a vicious circle.

[0003] On the other hand, menopausal women are under multiple pre...

Examples

Embodiment 1

[0030] The preparation of embodiment 1 Maca prescription

[0031] S1, the preparation of maca extract: get dry maca powder and cross 20 mesh sieves, process 150s under microwave power 2450HMz, add 70% (v / v) ethanol aqueous solution (note: each of the present invention) by solid-liquid ratio 1:10 The aqueous ethanol solutions in the examples are all represented by volume percentage), reflux extraction at 80°C for 2h, and filter to get the supernatant; add 90% ethanol aqueous solution to the filtered residue according to the ratio of material to liquid at 1:20, and reflux extraction at 95°C for 1h , filter to get the supernatant; merge the supernatant obtained twice, concentrate to a volume of 10% extract, add 5% starch by mass, make powder after drying, and pass through a 60-mesh sieve to obtain the maca extract ;

[0032] S2. Preparation of rehmannia glutinosa extract: mash the rehmannia glutinosa medicinal material into slices, add water according to the ratio of material to...

Embodiment 2

[0038] The preparation of embodiment 2 Maca prescription

[0039] S1, the preparation of maca extract: take dried maca powder and pass through 20 mesh sieves, process 150s under microwave power 2450HMz, add 90% ethanol aqueous solution according to material-liquid ratio 1:20, reflux extraction 1h under 95 ℃, filter and take supernatant; the filtered residue was added with 70% ethanol aqueous solution according to the ratio of material to liquid at 1:10, refluxed at 80°C for 2 hours, and filtered to get the supernatant; the supernatant obtained by combining twice was concentrated to a volume of 20% Paste, add the starch that mass percentage is 1%, make powder after drying, pass through 100 mesh sieves and obtain maca extract;

[0040] S2. Preparation of rehmannia glutinosa extract: mash the rehmannia glutinosa medicinal material into slices, add water according to the ratio of material to liquid at 1:15, extract at 100° C. for 2 hours, filter and get the supernatant; add water ...

Embodiment 3

[0046] The preparation of embodiment 3 Maca prescription

[0047] S1, the preparation of maca extract: take dry maca powder and cross 20 mesh sieves, process 150s under microwave power 2450HMz, add 80% ethanol aqueous solution by solid-liquid ratio 1:15, reflux extraction 1.5h under 90 ℃, filter and take The supernatant; the filtered residue was added with 75% ethanol aqueous solution according to the ratio of material to liquid 1:15, refluxed and extracted at 85°C for 1.5h, and the supernatant was filtered; the supernatant obtained by combining twice was concentrated to a volume of 15% The extractum of the extract, adding mass percentage is 2% starch, after drying, it is made into powder, and crosses 80 mesh sieves to obtain the maca extract;

[0048] S2. Preparation of rehmannia glutinosa extract: crush the rehmannia glutinosa medicinal material into slices, add water according to the ratio of material to liquid at 1:10, extract at 95°C for 1.5h, filter to get the supernatan...

technical field

[0001] The invention belongs to the field of traditional Chinese medicine health care products, and more specifically relates to a maca prescription for relieving menopausal symptoms of women and a preparation method thereof. Background technique

[0002] Menopause, also known as perimenopause, refers to the transitional stage of a woman's life from sexual maturity to old age, generally 45-55 years old. Ovarian dysfunction and decreased estrogen secretion lead to a series of symptoms such as endocrine dysfunction and autonomic nerve dysfunction in most menopausal women, resulting in paroxysmal hot flashes, fatigue, sweating, palpitations, insomnia, osteoarthritis, etc. Physical health problems such as porosity, accompanied by mental health problems such as depression, fear, and anxiety. At the same time, bad mental state interacts with autonomic dysfunction, easily forming a vicious circle.

[0003] On the other hand, menopausal women are under multiple pre...

Examples

Embodiment 1

[0030] The preparation of embodiment 1 Maca prescription

[0031] S1, the preparation of maca extract: get dry maca powder and cross 20 mesh sieves, process 150s under microwave power 2450HMz, add 70% (v / v) ethanol aqueous solution (note: each of the present invention) by solid-liquid ratio 1:10 The aqueous ethanol solutions in the examples are all represented by volume percentage), reflux extraction at 80°C for 2h, and filter to get the supernatant; add 90% ethanol aqueous solution to the filtered residue according to the ratio of material to liquid at 1:20, and reflux extraction at 95°C for 1h , filter to get the supernatant; merge the supernatant obtained twice, concentrate to a volume of 10% extract, add 5% starch by mass, make powder after drying, and pass through a 60-mesh sieve to obtain the maca extract ;

[0032] S2. Preparation of rehmannia glutinosa extract: mash the rehmannia glutinosa medicinal material into slices, add water according to the ratio of material to...

Embodiment 2

[0038] The preparation of embodiment 2 Maca prescription

[0039] S1, the preparation of maca extract: take dried maca powder and pass through 20 mesh sieves, process 150s under microwave power 2450HMz, add 90% ethanol aqueous solution according to material-liquid ratio 1:20, reflux extraction 1h under 95 ℃, filter and take supernatant; the filtered residue was added with 70% ethanol aqueous solution according to the ratio of material to liquid at 1:10, refluxed at 80°C for 2 hours, and filtered to get the supernatant; the supernatant obtained by combining twice was concentrated to a volume of 20% Paste, add the starch that mass percentage is 1%, make powder after drying, pass through 100 mesh sieves and obtain maca extract;

[0040] S2. Preparation of rehmannia glutinosa extract: mash the rehmannia glutinosa medicinal material into slices, add water according to the ratio of material to liquid at 1:15, extract at 100° C. for 2 hours, filter and get the supernatant; add water ...

Embodiment 3

[0046] The preparation of embodiment 3 Maca prescription

[0047] S1, the preparation of maca extract: take dry maca powder and cross 20 mesh sieves, process 150s under microwave power 2450HMz, add 80% ethanol aqueous solution by solid-liquid ratio 1:15, reflux extraction 1.5h under 90 ℃, filter and take The supernatant; the filtered residue was added with 75% ethanol aqueous solution according to the ratio of material to liquid 1:15, refluxed and extracted at 85°C for 1.5h, and the supernatant was filtered; the supernatant obtained by combining twice was concentrated to a volume of 15% The extractum of the extract, adding mass percentage is 2% starch, after drying, it is made into powder, and crosses 80 mesh sieves to obtain the maca extract;

[0048] S2. Preparation of rehmannia glutinosa extract: crush the rehmannia glutinosa medicinal material into slices, add water according to the ratio of material to liquid at 1:10, extract at 95°C for 1.5h, filter to get the supernatan...

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