Amino acid peritoneal dialysis fluid for dogs and cats and preparation method thereof

Abstract

The invention discloses an amino acid peritoneal dialysis solution for dogs and cats and a preparation method thereof, and belongs to the fields of animal husbandry, veterinarian and breeding industry. The peritoneal dialysis solution is composed of the following components by weight (for each 1000 mL): 1.0 to 2.0 grams of L-arginine, 1.0 to 1.6 grams of L-histidine, 0.6 to 0.9 gram of L-isoleucine, 1.3 to 1.5 grams of L-leucine, 0.8 to 1.0 gram of L-lysine, 0.4 to 0.6 gram of L-methionine, 0.7 to 0.8 gram of L-phenylalanine, 0.4 to 0.6 gram of L-threonine, 0.2 to 0.4 gram of L-tryptophan, 0.8 to 1.2 grams of L-valine, 0.1 to 0.3 gram of taurine, 0.2 to 0.3 gram of vitamin B6, 0.1 to 0.3 gram of astragalus polysaccharide, 0.1 to 0.3 gram of calcium chloride, and the balance being water for injection. The provided amino acid peritoneal dialysis solution can well relieve symptoms caused by kidney failure such as hyperitremia, hyperphosphatemia, hypoproteinemia, and the like, and can improve the ultrafiltration function of peritoneum and substance clearance rate.

Description

technical field

[0001] The invention belongs to the field of animal husbandry and veterinary breeding, and particularly relates to an amino acid peritoneal dialysis solution for treating renal failure in dogs and cats. Background technique

[0002] Renal failure is based on the occurrence of various kidney diseases. Due to the gradual damage of nephrons, the slow development of renal function decline leads to irreversible renal failure. The disease mainly manifests as decreased renal function, stagnation of metabolic waste (especially nitrogen-containing metabolites after protein decomposition), water, electrolyte and acid-base balance disorders, and various endocrine dysfunctions related to the kidneys, so that it cannot maintain A clinical syndrome caused by the stability of the internal environment of the body. In recent years, the problem of renal failure in dogs and cats has attracted more and more attention, and it is imperative to study new methods for effective trea...

Examples

Embodiment 1

[0032] An amino acid peritoneal dialysis solution for dogs and cats, every 1000 mL of the dialysis solution consists of the following components by weight: L-arginine 1.0 g, L-histidine 1.0 g, L-isoleucine 0.6 g, L- -Leucine 1.3 g, L-lysine 0.8 g, L-methionine 0.4 g, L-phenylalanine 0.7 g, L-threonine 0.4 g, L-tryptophan 0.2 g, L-valine Acid 0.8 g, taurine 0.1 g, vitamin B 6 0.2 g, astragalus polysaccharide 0.1 g and calcium chloride 0.1 g, and the balance is water for injection.

[0033] The specific steps for preparing each 1000 mL of dialysate are as follows:

[0034] (1) Use a graduated cylinder to measure an appropriate amount of water for injection and add it to a 1000 mL beaker;

[0035] (2) Weigh L-arginine, L-histidine, L-isoleucine, L-leucine, L-lysine, L-methionine, L-phenylalanine respectively according to the above weight Acid, L-threonine, L-tryptophan, L-valine, and taurine were added to the beaker, placed on a magnetic stirrer, and stirred to dissolve;

[...

Embodiment 2

[0040] An amino acid peritoneal dialysis solution for dogs and cats, every 1000 mL of the dialysis solution consists of the following components by weight: L-arginine 1.32 g, L-histidine 1.22 g, L-isoleucine 0.63 g, L- -Leucine 1.40 g, L-lysine 0.90 g, L-methionine 0.45 g, L-phenylalanine 0.72 g, L-threonine 0.58 g, L-tryptophan 0.20 g, L-valine Acid 0.80 g, taurine 0.20 g, vitamin B 6 0.20 g, astragalus polysaccharide 0.25 g and calcium chloride 0.15 g, and the balance is water for injection.

[0041] All the other are with embodiment 1.

Embodiment 3

[0043] An amino acid peritoneal dialysis solution for dogs and cats, every 1000 mL of the dialysis solution consists of the following components by weight: L-arginine 1.44 g, L-histidine 1.12 g, L-isoleucine 0.62 g, L- -Leucine 1.35 g, L-lysine 0.95 g, L-methionine 0.48 g, L-phenylalanine 0.70 g, L-threonine 0.48 g, L-tryptophan 0.25 g, L-valine Acid 0.88g, Taurine 0.25g, Vitamin B 6 0.25 g, astragalus polysaccharide 0.30 g and calcium chloride 0.20 g, and the balance is water for injection.

[0044] All the other are with embodiment 1.

technical field

[0001] The invention belongs to the field of animal husbandry and veterinary breeding, and particularly relates to an amino acid peritoneal dialysis solution for treating renal failure in dogs and cats. Background technique

[0002] Renal failure is based on the occurrence of various kidney diseases. Due to the gradual damage of nephrons, the slow development of renal function decline leads to irreversible renal failure. The disease mainly manifests as decreased renal function, stagnation of metabolic waste (especially nitrogen-containing metabolites after protein decomposition), water, electrolyte and acid-base balance disorders, and various endocrine dysfunctions related to the kidneys, so that it cannot maintain A clinical syndrome caused by the stability of the internal environment of the body. In recent years, the problem of renal failure in dogs and cats has attracted more and more attention, and it is imperative to study new methods for effective trea...

Examples

Embodiment 1

[0032] An amino acid peritoneal dialysis solution for dogs and cats, every 1000 mL of the dialysis solution consists of the following components by weight: L-arginine 1.0 g, L-histidine 1.0 g, L-isoleucine 0.6 g, L- -Leucine 1.3 g, L-lysine 0.8 g, L-methionine 0.4 g, L-phenylalanine 0.7 g, L-threonine 0.4 g, L-tryptophan 0.2 g, L-valine Acid 0.8 g, taurine 0.1 g, vitamin B 6 0.2 g, astragalus polysaccharide 0.1 g and calcium chloride 0.1 g, and the balance is water for injection.

[0033] The specific steps for preparing each 1000 mL of dialysate are as follows:

[0034] (1) Use a graduated cylinder to measure an appropriate amount of water for injection and add it to a 1000 mL beaker;

[0035] (2) Weigh L-arginine, L-histidine, L-isoleucine, L-leucine, L-lysine, L-methionine, L-phenylalanine respectively according to the above weight Acid, L-threonine, L-tryptophan, L-valine, and taurine were added to the beaker, placed on a magnetic stirrer, and stirred to dissolve;

[...

Embodiment 2

[0040] An amino acid peritoneal dialysis solution for dogs and cats, every 1000 mL of the dialysis solution consists of the following components by weight: L-arginine 1.32 g, L-histidine 1.22 g, L-isoleucine 0.63 g, L- -Leucine 1.40 g, L-lysine 0.90 g, L-methionine 0.45 g, L-phenylalanine 0.72 g, L-threonine 0.58 g, L-tryptophan 0.20 g, L-valine Acid 0.80 g, taurine 0.20 g, vitamin B 6 0.20 g, astragalus polysaccharide 0.25 g and calcium chloride 0.15 g, and the balance is water for injection.

[0041] All the other are with embodiment 1.

Embodiment 3

[0043] An amino acid peritoneal dialysis solution for dogs and cats, every 1000 mL of the dialysis solution consists of the following components by weight: L-arginine 1.44 g, L-histidine 1.12 g, L-isoleucine 0.62 g, L- -Leucine 1.35 g, L-lysine 0.95 g, L-methionine 0.48 g, L-phenylalanine 0.70 g, L-threonine 0.48 g, L-tryptophan 0.25 g, L-valine Acid 0.88g, Taurine 0.25g, Vitamin B 6 0.25 g, astragalus polysaccharide 0.30 g and calcium chloride 0.20 g, and the balance is water for injection.

[0044] All the other are with embodiment 1.

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