43 results about "Balance disorders" patented technology

A system for treating patients affected both by hearing loss and by balance disorders related to vestibular hypofunction and / or malfunction, which includes sensors of sound and head movement, processing circuitry, a power source, and an implantable electrical stimulator capable of stimulating areas of the cochlea and areas of the vestibular system.

A system for treating patients affected both by hearing loss and by balance disorders related to vestibular hypofunction and / or malfunction, which includes sensors of sound and head movement, processing circuitry, a power source, and an implantable electrical stimulator capable of stimulating areas of the cochlea and areas of the vestibular system.

A system and method for providing therapy and assessment utilizing vibrotactile feedback is disclosed. Such treatment is useful for the assessment and treatment of disequilibrium, movement and balance disorders. The system and method measures a subject's performance of predetermined tasks with respect to expected parameters using sensors such as force plates, inertial sensors, and three dimensional cameras. Predetermined motions are motions such as stand, sit-to-stand, reach, bend, functional gait, functional gait plus headshake, and other functional tasks. Vibrotactile stimulation may be applied during the subject's performance as disruptive input. Variance and rate of change of variance between measured and expected parameters is used as a tool for assessment of said subject, and is also used for providing real-time vibrotactile training to said subject. The invention is useful in the treatment of Traumatic Brain Injury (TBI), neurologic disorders causing disequilibrium and balance disorders, and the like.

A system for treating patients affected both by hearing loss and by balance disorders related to vestibular hypofunction and / or malfunction, which includes sensors of sound and head movement, processing circuitry, a power source, and an implantable electrical stimulator capable of stimulating areas of the cochlea and areas of the vestibular system.

A method and apparatus is disclosed for providing motional training, such as treatment of disequilibrium and movement and balance disorders, using cognitive spatial activity and by providing a subject with vibrotactile feedback in response to an attempt to perform the spatial activity.

Compositions and methods are provided for prophylactic or therapeutic treatment of a mammal for hearing or balance impairments involving neuronal damage, loss, or degeneration, preferably of spiral ganglion neurons, by administration of a therapeutically effective amount of one or more molecules having erythropoietin activity selected from EPO, or a biosimilar, a variant, or a mutant thereof; a protein or peptide mimetic of EPO; a small molecule mimetic of EPO and an erythropoiesis stimulating agent. Also provided are improved compositions and methods for treatments of ototoxicity requiring administration of a pharmaceutical having an ototoxic side-effect in combination with a therapeutically effective amount of a molecule having erythropoietin activity.

A system and method for providing therapy and assessment utilizing vibrotactile feedback is disclosed and claimed. Such treatment is useful for the treatment of disequilibrium and balance disorders. The system and method uses sensors such as force plates, inertial sensors, and three dimensional cameras to provide a subject with vibrotactile feedback in response to an attempt by the subject to perform predetermined motions. Predetermined motions are motions such as stand, sit-to-stand, reach, bend, functional gait, functional gait plus headshake, and other functional tasks. Vibrotactile stimulation may be applied during the subject's performance of a functional gait task as a disruptive input. Variance and rate of change of variance between measured and expected parameters are determined and used as a tool for assessment, and may also be used for providing real-time vibrotactile training. Such assessment and therapy is useful in the treatment of Traumatic Brain Injury (TBI).

A system for treating patients affected both by hearing loss and by balance disorders related to vestibular hypofunction and / or malfunction, which includes sensors of sound and head movement, processing circuitry, a power source, and an implantable electrical stimulator capable of stimulating areas of the cochlea and areas of the vestibular system.

This invention relates to compounds, compositions, and methods useful for modulating retinoblastoma (RB1) gene expression using short interfering nucleic acid (siNA) molecules. This invention also relates to compounds, compositions, and methods useful for modulating the expression and activity of other genes involved in pathways of retinoblastoma gene expression and / or activity by RNA interference (RNAi) using small nucleic acid molecules. In particular, the instant invention features small nucleic acid molecules, such as short interfering nucleic acid (siNA), short interfering RNA (siRNA), double-stranded RNA (dsRNA), micro-RNA (miRNA), and short hairpin RNA (shRNA) molecules and methods used to modulate the expression of retinoblastoma genes. Such small nucleic acid molecules are useful, for example, for treating, preventing, inhibiting, or reducing hearing loss, deafness, tinnitus, motion and balance disorders, cancer and proliferative diseases and any other disease, condition, trait or indication that can respond to the level of retinoblastoma in a cell or tissue, alone or in combination with other treatments or therapies.

Compositions and methods are provided for prophylactic or therapeutic treatment of a mammal for hearing or balance impairments involving neuronal damage, loss, or degeneration, by administration of a therapeutically effective amount of a redox-active therapeutic. Also provided are improved compositions and methods for treatments requiring administration of a pharmaceutical having an ototoxic side-effect in combination with a therapeutically effective amount of a redox-active therapeutic to treat the ototoxicity.

The invention provides a human body balance assessment system and assessment method. The human body balance assessment system includes a man-machine interaction module, an action comparison module, a plantar pressure detection module, and a balance index quantification module. The human body balance assessment method includes: setting an application scene in the man-machine interaction module, allowing interactive actions between the human body and the application scene, using a somatosensory sensor to record three-dimensional coordinates of corresponding nodes of a human body skeleton model in real time, and using a plantar pressure sensor to measure the plantar pressure in real time; calculating the angles of human body joints, and determining if the action is standard or not; performing pretreatment on the plantar pressure value if so, and calculating the plantar pressure center; and assessing the balance ability of a human body according to the offset degree of the plantar pressure center. The somatosensory sensor and the plantar pressure sensor are combined; standard actions with different difficulties are designed for people groups with different balance disorders; the objectivity and the reliability of balance assessment can be improved; and the human body balance assessment system and assessment method has wide application value.

A system for use by a clinician to perform an emergency diagnosis of a patient for a balance disorder includes a position sensor and an optical sensor that are mounted on a base member. The base member is configured to be fixedly held over the eyes of the patient during a predetermined diagnostic maneuver of the head of the patient. A processor having electronic memory is included which receives outputs from the optical sensor and the position sensor. A set of instructions constituting an eyetracker computer program is processed by the computer. Quantified eye movement data and a video stream signal can be displayed on a visual display that is affixed to the base member for observation by the clinician and recorded in computer readable memory.

The invention discloses a household and hospital portable rehabilitation training system and method realizing vestibular rehabilitation based on VR equipment. The training system comprises a scale evaluation module, the VR equipment, a positioning sensor, a training self-evaluation module and a training storage module, the scale evaluation module includes a vertigo and balance disorder scale usedto test the level of condition of a trainee, the VR equipment includes training videos for rehabilitation of vestibular disorder, the training videos are divided into training levels corresponding tothe condition levels, the positioning sensor is connected with both the VR equipment and the training self-evaluation module and used to sense the rehabilitation training condition of different body parts of the trainee and send a sensing result to the self-evaluation module, and the training self-evaluation module provides a self-evaluation score according to the received sensing result. The system can be used both at home and in hospital. The invention also discloses a training method at the same time.

The present invention relates to methods for treating or preventing intestinal fluid balance disorders and modulating intestinal fluid secretion and absorption using calcimimetics and calcilytics.

The invention discloses a mobile terminal. The mobile terminal comprises a memory, a processor and a photo shooting lighting program which is stored on the memory and can run on the processor, whereinthe photo shooting lighting program is executed by the processor through the following steps of detecting ambient brightness when a shooting instruction is detected, judging whether the ambient brightness is smaller than a preset brightness threshold value, and if a judgment result is yes, starting a lighting function to increase the ambient brightness. After the ambient brightness is enhanced, ashot picture is brighter and clearer, and a flash lamp is not needed after the ambient brightness is enhanced, the conditions such as white balance disorder, main body overexposure, dark surroundingand influence of halation on facial expression cannot occur, and the technical problem that photo shooting through the existing mobile terminal is poor in photographing effect under the condition thatthe ambient light intensity is low or the flash lamp is used is solved. The invention further provides a photo shooting lighting method and a computer readable storage medium.

The invention discloses a method for distinguishing the crowd with balance disorder based on a center of gravity shift model. The method comprises the following steps: firstly, human walking posture video of a normal person and an abnormal person in a built virtual reality scene is collected from 45 DEG; then, the video of normal person and abnormal person is loaded, the video image is extracted into pictures, and then the pictures are processed to obtain the barycenter coordinates of normal person and abnormal person respectively, finally, according to the center of gravity data, the center of gravity angle data and the mean and variance of the upper and lower center of gravity of human body are extracted, and the center of gravity data are classified by SVM classifier, and then combinedwith the center of gravity angle data and the mean and variance of the upper and lower center of gravity of human body, the balance ability disorder crowd is quickly judged. The method disclosed by the invention solves the problems that the traditional subjective method is too coarse and the gauge evaluation method is too complex and the cost is too high, and the video and the image are processedthrough a plurality of steps, and the final classification accuracy rate is above 85%.

The invention discloses a method for distinguishing human body balance obstacles based on a gravity center area model under visual stimulation. The method comprises the following steps of firstly shooting a human body walking posture video of a normal person and an abnormal person in an established simulated reality scene according to an angle of 90 degrees with the front face when the human bodywalks; secondly, respectively extracting acquired walking posture videos of the normal person and the abnormal person into pictures, and respectively processing the extracted pictures to obtain upper,middle and lower gravity center coordinate data of the normal person and the abnormal person; and finally, judging and classifying the crowd with the balance ability disorder by combining the gravitycenter area data, the triangular area mean square error, the speed and the track route map. According to the method, the tumbler principle is used for explaining the crowd with the balance obstacle capability through the gravity center area deviation model, so that the balance capability of the crowd or other people is objectively judged, videos and images are processed through a plurality of steps, and the final classification accuracy is ensured to be 86% or above.

The present invention relates to a diagnostic or training apparatus including a controller, a balance pad connected to the controller and receiving information from the controller, and a patient support, the balance pad being located within the patient support. A patient support and method are also provided.

Provided are compositions and methods comprising PI3K agonists for increasing proliferation of cochlear supporting cells or vestibular supporting cells, and related methods of treating hearing or balance disorders.

A system and associated method for computerized rotational head impulse test (crHIT) to assess the semicircular canals of the human vestibular system clinically in patients with balance disorders. The system utilizes a rotary chair combined with a head mounted VOG system with head tracking sensors. The crHIT protocol uses the same physiologic principles as the known video head impulse test (vHIT). The crHIT utilizes whole-body rotation via the chair to yield a persistent controlled, repeatable, comfortable, reliable stimulus can be delivered while recording eye movements with video-oculogaphy.

Disclosed herein is use of one or more aminopyridines in methods and compositions for treatment of impairments in gait or balance in patients with multiple sclerosis.

The invention relates to the technical field of clinical medicine, in particular to a precise sodium adjusting method for a displacement liquid formula. For patients with metabolic acidosis or withoutacid-base balance disorders, the amount I1 of 10% sodium chloride solution added to an initial displacement liquid can be obtained by a formula 1 and a formula 2, and for patients with metabolic alkalosis, the amount I6 of 10% sodium chloride solution added to the initial displacement liquid can be obtained by a formula 7 and a formula 8. The simple and easy-to-master formulas are adopted, the sodium ion concentration of the displacement liquid is precisely adjusted to achieve a controlled sodium reduction effect, the sodium reduction effect is accurate, the sodium reduction is balanced and stable every hour, and the sodium is adjusted individually according to different patients, the anti-coagulation problem in CRRT treatment for severe hypernatronemia accompanied by active bleeding patients is solved, meanwhile, the occurrence of complications during the anticoagulation process is prevented, balanced and stable sodium reduction is realized, and the occurrence of cerebral edema is reduced.

The invention relates to medicine technical field, in particular to a sylvite compound of entecavir, a relative preparation method and medical application thereof. The invention dissolves entecavir in a tic potash water solution to be reacted, deposits via unit alcohol or ketone with low carbon chains, dries and purifies to obtain the product. The entecavir sylvite has high solubility, for supporting drug preparation and improving drug bioavailability. The entecavir sylvite can improve the sylvite supplementary of hepatopath and adjust electrolyte balance disorder of hepatitis patient, with high clinical value.

The invention provides a new clinical uses for treatment of Th1 / Th2 balance disorder by medicine composition wherein foscarnet sodium as active component, particularly use for Th1 / Th2 balance disorder caused by in treatment of hepatitis b virus.

The liposome dimethylcurcumin is a liposome-encapsulated dimethylcurcumin (Lipo-DiMC). Dimethyl curcumin is a synthetic curcumin analog with the chemical formula C23H24O6. Compared with curcumin and dimethyl curcumin, Lipo- DiMC has better metabolic stability and is highly water soluble and has a sustained release effect in vivo. In some inflammatory, autoimmune and cancer diseases, Dipeptidyl peptidase (DPPI) and Matrix metalloproteinase (9, MMP-9) are overexpressed, leading to changes in tissue microenvironment and in vivo. Balance disorders and cause cell reproductive disorders. In the ratmodel of collagen induced arthritis (CIA) treated with Lipo-DiMC, Lipo-DiMC alleviated the swelling of the toes of CIA rats and inhibited DPPI and MMP in body fluids, blood and spleen lymphocytes of CIA rats-9 Overexpression of activity. The in vitro rat spleen lymphocyte model further confirmed that Lipo-DiMC inhibited and regulated the DPPI activity and MMP 9 expression and secretion in rat spleen lymphocytes.

The invention provides a new clinical uses for treatment of Th1 / Th2 balance disorder by medicine composition wherein foscarnet sodium as active component, particularly use for Th1 / Th2 balance disorder caused by in treatment of hepatitis b virus.

The invention provides a thermal tandem rolling machine control device which maximally exert equipment capability and suppress speed balance disorder between rolling frames in rolling, and a thermal tandem rolling machine control method. A thermal tandem rolling machine (151) is used as a control object, a structure which is described is adopted in the thermal tandem rolling machine control device (100) in which workpiece rollers (153) that are equipped in a plurality of rolling frames (152) continuously control rolling of a steel plate. The thermal tandem rolling machine control device aims at different risks of reaching an upper limit of a rolling speed according to steel plate characteristic and can set a speed allowance for each steel plate, thereby appropriating a maximal value of the rolling speed which can be set by setting operation. Hereon, preferably, when the rolling speed of a specific rolling frame (152) in rolling reaches the upper limit of the rolling speed, controlling is performed for reducing the rolling speed of each rolling frame (152), thereby minimizing speed balance disorder among the rolling frames (152).

A compound of Formula (I)) or a pharmaceutically acceptable salt thereof, is provided that has been shown to be useful for treating hearing loss or balance disorder:wherein R1 through R3, and L are as defined herein.

The present invention relates to methods for treating intestinal fluid balance disorders and modulating intestinal fluid secretion and absorption using calcimimetics and calcilytics.

The anatomic and functional arrangement of the gastrointestinal tract suggests an important function of this organ is its ability to regulate the trafficking of metabolites as well as control the equilibrium between tolerance and immunity through gut-associated lymphoid tissue, the neuroendocrine network, and the intestinal epithelial barrier. Combining nucleated cells from various tissues and introducing them directly into the small intestine will have a positive effect on diabetes.