3 results about "Sterile water solution" patented technology

A bone gel composition comprising cortical bone is provided. The cortical bone is made from cut pieces freeze-dried then ground into particles and demineralized then freeze-dried. A volume of the particles is placed in a solution of sterile water to create a mixture, the water volume being twice the second portion, the mixture is autoclaved under heat and pressure to form a gelatin, the resulting bone gel is placed in jars and kept at room temperature or frozen for later use. The cortical bone has the cut pieces having a width, a length and a thickness in the range of 1 to 4 mm. The cortical bone pieces are ground to a particle size up to 125 microns.

A solid cannabinoid composition comprising: (i) 0.3 to 10% by weight of one or more cannabinoids; (ii) 4 to 69% by weight of one or more nonionic surfactants having an HLB value of 10 to 25; (iii) at least 20% by weight of one or more carbohydrates selected from mannitol, sucrose, trehalose, and stachyose; and (iv) 0 to 5% by weight of water, wherein the combination of one or more nonionic surfactants and one or more carbohydrates accounts for at least 70% by weight of the composition. A sterile aqueous solution for use in medical treatment, comprising: (a) 0.1 to 10 mg / mL of one or more cannabinoids; (b) one or more nonionic surfactants having an HLB value of 10 to 25; (c) one or more carbohydrates selected from mannitol, sucrose, trehalose, and stachyose; and (d) at least 85% by weight of water, wherein one or more nonionic surfactants and one or more cannabinoids are present in the sterile aqueous solution in a weight ratio of 3:1 to 30:1, and one or more carbohydrates and one or more cannabinoids are present in the sterile aqueous solution in a weight ratio of 3:1 to 300:1.

The invention discloses a method for establishing a stable damp-heat ulcerative colitis animal model. A DSS, high-glucose and high-fat diet and artificial climate box combined induced damp-heat type ulcerative colitis model is adopted, and the method comprises the following steps: (1) high-glucose and high-fat diet: mice freely eat high-glucose and high-fat feed from the first day until an experiment is finished; (2) artificial climate box treatment: from the eleventh day, putting the mice into an artificial climate box with the temperature of 35 DEG C and the humidity of 90% for 6-8 hours every day; the mouse is not placed in the artificial climate box during DSS induction; and (3) DSS treatment: starting from the 21st day, the mice freely drink a DSS sterile aqueous solution for 7 days, then the mice are put into the artificial climate box in the step (2) to freely drink water for 7 days to serve as a recovery period, high-glucose and high-fat feeding is adopted in the period, the period is a molding period, and the period is performed for 3 periods. The built model is similar to ulcerative colitis in traditional Chinese medicine clinical symptoms and signs, good in repeatability and stability and suitable for traditional Chinese medicine screening for treating ulcerative colitis through a traditional Chinese medicine heat clearing and diuresis promoting method.