The invention discloses a self-cleaning lamination permeation water purifier, comprising a shell and a filter element as well as an inner bushing, wherein the filter element is formed by mutual stacking of at least more than two filtration laminations with center holes, a clearance used for filtering impurities in water is formed between the laminations, the filtration laminations are stacked up in the inner bushing, a pressing plate is arranged at the top end of the inner bushing, criss-cross annular grooves are formed in the surface of the outer circumference of the inner bushing, the annular grooves are communicated with a pure water outlet in the shell, a pressing cap for pressing the pressing plate and the filter element is arranged at the top end of the shell, and a descaling device used for cleaning the filtration lamiantions is arranged in the shell. By adopting the structure, while the water purification effect is ensured, on one hand, installation and dismounting are facilitated due to the inner bushing during installation, and the installation and dismounting efficiency is improved, on the other hand, the structure design is reasonable, the manufacture is easy and convenient, material consumption is reduced compared with conventional water purifiers, and the manufacture cost is lowered.