The invention relates to the field of mills, and discloses a cylinder structure of a large modular mill. The cylinder structure comprises a plurality of cylinders which are connected with one another,the two ends of each cylinder are connected with end flanges correspondingly, the outer surface of each cylinder is sleeved with at least one annular flange, and one side of each cylinder is connected with an excitation device mounting base through the at least one annular flange; the other side of each cylinder is connected with a balance weight through the at least one annular flange, and the balance weights are used for adjusting the weight of the two sides of the cylinders; and spring bases are arranged at the lower ends of the two sides of each cylinder correspondingly. According to thecylinder structure of the large modular mill, through horizontal arrangement of a vibratory mill, dry-process and wet-process ore grinding can be achieved, the excitation device is arranged on one side of each cylinder, the balance weight is arranged on the other side of each cylinder, the cylinder structure is provided with the spring bases and supported by springs, the large scale of the mill iswell completed, machining, manufacturing and transporting are convenient, modular design of the mill is achieved, and the cylinder structure has the excellent characteristics of high ball loading rate, low energy consumption and universality for dry milling and wet milling and the like.