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Compound traditional Chinese medicinal prepn. for preventing and treating uterus abnormal bleeding disease, and its prepn. method

The technology of a compound preparation and production method is applied in the field of production of traditional Chinese medicine compound preparations for preventing and treating abnormal uterine bleeding.

Active Publication Date: 2007-08-29
ZHEJIANG ASEN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The treatment of traditional Chinese medicine on menstrual abnormalities caused by IUD has been scattered in recent years, but most of the cases are small in number, and most of them are clinical observations without objective indicators. The dosage forms are mostly water decoctions, and there is no special treatment for this disease Therefore, it is an important topic at present to study therapeutic drugs with high curative effect, no side effects, and easy to take to improve the utilization rate of IUD.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] 54.6g Panax notoginseng is crushed into particles with a size of 5-10mm, added with 50% ethanol to reflux and extracted twice, the first time is 1.5 hours, the second time is 1 hour, the extracts are combined, filtered, and the filtrate is decompressed to recover ethanol, and it is used for later use; Slag and 136.5g madder, 109.2g Puhuang, 273g Burnet, 81.9g Scutellaria baicalensis, 136.5g Rehmannia glutinosa, 273g Agrimony, 273g sea octopus, 163.8g Codonopsis pilosula, 136.5g white peony root, 54.6g licorice and decocted twice, Combine the decoction for 1.5 hours for the first time and 1 hour for the second time, filter, concentrate the filtrate to a clear paste with a relative density of 1.06-1.08 (60°C), let it cool, add ethanol to make the alcohol content 30%, and refrigerate for 12 hour, filter, the filtrate is decompressed to recover ethanol, combined with the Panax notoginseng extract, and concentrated under reduced pressure to a clear paste with a relative densi...

Embodiment 2

[0024] 101.4g Panax notoginseng is crushed into particles with a size of 5-10mm, added with 90% ethanol to reflux and extracted twice, the first time is 3.5 hours, the second time is 3 hours, the extracts are combined, filtered, and the filtrate is decompressed to recover ethanol, and set aside; Slag and 253.5g madder, 202.8g Puhuang, 507g Burnet, 152.1g Scutellaria baicalensis, 253.5g Rehmannia glutinosa, 507g Agrimony, 507g sea octopus, 304.2g Codonopsis pilosula, 253.5g Radix Paeoniae Alba, 101.4g licorice and decoct twice, Combine the decoction for 3.5 hours for the first time and 3 hours for the second time, filter, concentrate the filtrate to a clear paste with a relative density of 1.06-1.08 (60°C), let it cool, add ethanol to make the alcohol content 70%, and refrigerate for 36 hour, filter, the filtrate is decompressed to recover ethanol, combined with the Panax notoginseng extract, concentrated under reduced pressure to a clear paste with a relative density of 1.06 to...

Embodiment 3

[0026]78g Panax notoginseng is crushed into particles of 5-10mm in size, added 70% ethanol to reflux and extracted twice, the first time is 2 hours, the second time is 1.5 hours, the extracts are combined, filtered, the filtrate is decompressed to recover ethanol, and the dregs are used for later use; With 195g madder, 156g Puhuang, 390g Burnet, 117g Scutellaria baicalensis, 195g Rehmannia glutinosa, 390g Agrimony, 390g sea octopus, 234g Codonopsis pilosula, 195g white peony root, 78g licorice and decoct twice, the first time for 2 hours, the second time Combine the decoction for 1.5 hours, filter, concentrate the filtrate to a clear paste with a relative density of 1.06-1.08 (60°C), let it cool, add ethanol to make the alcohol content 50%, refrigerate for 24 hours, filter, and decompress the filtrate Recover ethanol, combine it with Panax notoginseng extract, concentrate under reduced pressure to a clear paste with a relative density of 1.06-1.10 (60°C), add an appropriate amo...

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Abstract

A Chinese medicine in the form of particles for preventing and treating the abnormal metrorrhagia is prepared from 11 Chinese-medicinal materials including notoginseng, rehmannia root, pilose asiabell root, white peony root, etc. Its preparing process is also disclosed.

Description

technical field [0001] The invention relates to a production method of a traditional Chinese medicine compound preparation for preventing and treating abnormal uterine bleeding. Background technique [0002] The family planning work is the basic state policy of our country. Strictly controlling population growth is a fundamental plan related to the prosperity of the country, the prosperity of the nation, and the happiness of future generations. Actively preventing complications of birth control measures is an important aspect of family planning work. About 50% (more than 80 million people) of my country's women of childbearing age use the intrauterine device (IUD) for contraception. It has the advantages of safety, simplicity, long-term effect, and economy. Side effects such as irregular bleeding have become the main reason for taking the device. In recent years, antifibrinolytic, antiprostaglandin and other hemostatic drugs are often used at home and abroad, but it is stil...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/88A61K36/804A61K36/74A61K36/739A61K36/73A61K36/71A61K36/539A61K36/344A61K35/56A61K9/16A61K9/20A61K9/48A61P15/00A61P7/04A61K35/618
Inventor 刘瑞芬
Owner ZHEJIANG ASEN PHARMA
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