Blood-activating collaterals-dredging composition for repair internal fistula after puncture and preparation method thereof and formulations

A technology for activating blood and dredging collaterals and a composition, which is applied in the field of traditional Chinese medicine, can solve the problems of adverse effects of post-operative rehabilitation of internal fistulas, influence on post-operative nursing care of arteriovenous internal fistulas, unsatisfactory effects of pain relief, and the like. Ensure long-term effective use, avoid volatile oil loss or oxidation, and promote the effect of internal fistula maturation

Pending Publication Date: 2020-11-06
钦州市第一人民医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there will be some complications after the arteriovenous fistula operation, such as vascular stenosis, thrombosis, etc. The emergence of these complications will directly affect the postoperative care of the arteriovenous fistula operation, and affect the patient's postoperative rehabilitation and internal fistula. Maturity adversely affects
[0003] Secondly, the hematoma that occurs during the use of the internal fistula seriously affects its use.
For the treatment of internal fistula hematoma, at present clinical practice usually uses towel hot compress after 24 hours of pulling out the needle. After the hot compress, apply polysulfonic acid mucopolysaccharide cream on the hematoma and massage gently for 5-10 minutes until the ointment is completely absorbed through the skin. 3-4 times a day, the effect of hematoma dissipation and pain relief is not very satisfactory, especially for those with larger hematoma area, the effect is very little

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] The medicinal wine for promoting blood circulation and dredging collaterals for the repair of arteriovenous fistula after puncture is made from the following traditional Chinese medicine raw materials: 10kg of safflower, 5kg of Sanqi, 10kg of peach kernel, 10kg of myrrh, 10kg of frankincense, and 10kg of curcuma. Crush the above raw materials of traditional Chinese medicine, add 50% rice wine at a volume ratio of 1:1, seal and soak for 30 days, and filter to obtain.

Embodiment 2

[0039] The medicinal wine for promoting blood circulation and dredging collaterals for repairing arteriovenous fistula after puncture is made from the following traditional Chinese medicine raw materials: 5kg of safflower, 2kg of notoginseng, 5kg of peach kernel, 5kg of myrrh, 15kg of frankincense, and 15kg of zedoary.

[0040] The specific preparation method is as follows:

[0041] (c1) Pulverize myrrh and frankincense into coarse powder, use absolute ethanol as solvent, percolate at a flow rate of 2ml / min after soaking for 18h, collect 10 times the amount of filtrate, centrifuge, leave to stand for stratification, and take the supernatant Sealed to obtain volatile oil alcohol solution;

[0042] (c2) Mix the dregs of step (c1) with other raw materials, add 3 times the amount of water, reflux and extract 3 times at 75°C, each time distribution is 4h, 2h, 1h, combine the extracts, filter, and Concentrate at 50°C, cool to room temperature, mix evenly with the volatile oil alcoh...

Embodiment 3

[0044] A Huoxuetongluo ointment for arteriovenous fistula puncture repair, made of the following traditional Chinese medicine raw materials: 5kg of safflower, 2kg of Sanqi, 5kg of peach kernel, 5kg of myrrh, 15kg of frankincense, and 15kg of curcuma.

[0045] The specific preparation method is as follows:

[0046] (a1) Take the above-mentioned traditional Chinese medicine raw materials, grind them into powders with a particle size of 500 μm, put them in a high-pressure tank and add absolute ethanol three times the total weight of the traditional Chinese medicine raw materials, keep the pressure at 22 °C and 12 MPa for 3 minutes, and then put the high-pressure tank Release the pressure to normal pressure within 35s, and separate the medicine residue and medicine liquid in the high-pressure tank;

[0047] (a2) Take the dregs, add water and extract twice under reduced pressure, the amount of water added each time is 6 times and 3 times the total weight of the dregs, and the extra...

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PUM

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Abstract

The invention discloses a blood-activating collaterals-dredging composition for repairing an internal fistula after puncture. The composition is prepared from flos carthami, pseudo-ginseng, peach kernel, myrrh, frankincense and rhizoma curcumae. The composition can be prepared into medicinal liquor or other external formulations such as gels, ointments and tinctures. Based on the principle of combining traditional Chinese medicine theory and Western medicine theory, the composition of the present invention is scientifically compatible, so that various medicinal materials can cooperate with each other, make up for deficiencies of each other, and has the effects of promoting blood circulation, removing blood stasis, reducing swelling, relieving pain, convergence and promoting tissue regeneration. The composition can be used for patients with local stagnation of Qi and blood, venous obstruction and collateral stasis before and after the internal arteriovenous fistula operation. The composition allows internal arteriovenous fistula vessels to be nourished, full of Qi and blood and unobstructed, reduces complications such as hemadostenosis, angiosteosis, hematoma and thrombosis, promotes the maturity of the internal fistula, and guarantees the long-term effective use of the internal arteriovenous fistula in maintenance hemodialysis patients. The composition has the advantages of quick action, little side effects due to local administration, high safety, and convenient use.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a composition for promoting blood circulation and dredging collaterals for repairing internal fistula after puncture, a preparation method and a preparation. Background technique [0002] Hemodialysis is the main method of kidney replacement for patients with chronic kidney disease in the uremic phase. More than 80% of hemodialysis patients have arteriovenous access. Arteriovenous fistula is the lifeline of maintenance hemodialysis patients. A well-functioning arteriovenous Internal fistula is of great significance to the survival of hemodialysis patients. Arteriovenous fistula is an anastomosis of adjacent arteries and veins on the patient's forearm by the doctor to make it a blood flow channel. The arteriovenous fistula requires superficial arteries and veins, and the operation is easy to operate. After the internal fistula matures, the veins In the event of arteria...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P9/00A61P7/10A61P7/00
CPCA61K9/0014A61K36/258A61K36/286A61K36/324A61K36/328A61K36/736A61K36/9066A61K2236/33A61K2236/331A61K2236/333A61K2236/39A61K2236/53A61P7/00A61P7/10A61P9/00A61K2300/00
Inventor 钟晓明许雪芳
Owner 钦州市第一人民医院
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