The invention provides a directional enrichment method of
traditional Chinese medicine hypoglycemic active ingredients. The preparation method comprises the following steps: 1, mixing iron stick yam,
rehmannia root, dwarf lilyturf tuber and
dendrobium officinale, adding dried orange peel
powder, carrying out
superfine grinding, and collecting superfine
powder with D50 of 15-25 [mu] m; 2, adding deionized water into the
powder, stirring for 20-25 minutes to form
slurry, adding 4-5% of honey, and continuously stirring for 10-15 minutes; 3, adding
bifidobacterium probiotic powder, and standing for 20-25 minutes until the pH value of the
system is 5.0-5.2; 4, adding a compound
enzyme preparation, and carrying out enzymolysis for 3-3.5 hours at the temperature of 50 DEG C and the speed of 100-120rpm; 5, the temperature is raised to 95 DEG C,
enzyme deactivation is conducted for 10 min,
centrifugation is conducted for 20 min at 7500-8500 rpm, and supernate is taken; and 6, concentrating under reduced pressure until the
solid content is 15-20%, and freeze-
drying. According to the method disclosed by the invention,
superfine grinding, targeted enzymolysis and natural stabilization technologies are organically fused to form an integrated process of
carbon source supply,
probiotic proliferation,
pH regulation,
active ingredient reduction and wall-breaking synergism, so that an efficient directional enrichment
system is constructed, and efficient enrichment, activity activation and stable retention of the
traditional Chinese medicine hypoglycemic active ingredients are realized.