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Medicine for animals for treating and preventing avian influenza

A bird flu and veterinary drug technology, applied in pharmaceutical formulas, medical preparations containing active ingredients, peptide/protein components, etc., can solve problems affecting the quality and hygiene of meat and eggs, intestinal damage of livestock and poultry, and poor treatment effects, etc. , to achieve the effect of preventing and treating avian influenza, reducing the incidence rate, and improving the repair function of intestinal damage

Inactive Publication Date: 2012-06-06
西安亨通光华制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the disease can be controlled and improved by using other drugs, it can only treat the symptoms but not the root cause, and can only control the disease. The recurrence rate is high and drug residues are caused, which seriously affects the quality and hygiene of meat and egg food
Enteritis (viral, bacterial, fungal, parasitic) is a common and frequently-occurring disease in animals. There are many drugs for treating simple enteritis, and most of them have good curative effects. However, enteritis in animals often recurs or Mixed outbreaks cause severe intestinal damage in livestock and poultry, coupled with repeated use of antibiotics, the treatment effect is not good, the course of the disease is lengthy, and even the prognosis is poor, causing huge losses to the animal husbandry industry
At present, drugs for repairing intestinal damage are rare, and only some intestinal mucosal protective agents are used, but their curative effect is not obvious

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0065] Embodiment 1: Take the mannan-peptide-containing mannan-peptide produced by the space-induced mutagenesis strain at a weight ratio of 0.5 mg / ml, 1000 ml of a mannan-peptide solution with a pH of 4.0-6.0, add 0.25 g of activated carbon, stir well, filter, and add Sodium saccharin 0.1g, add essence 0.1ml, stir well, fill and seal to make: 100ml / bottle, 250ml / bottle, 500ml / bottle, 1000ml / bottle, 2000ml / bottle, 5000ml / bottle, 10000ml / bottle, 20000ml The α-mannan peptides of different packaging specifications per bottle are sterilized by circulating steam at 121° C. for 30 minutes, inspected by light, packaged, and put into the market after passing the inspection. The specific operation is as described above.

Embodiment 2

[0066] Example 2: basically the same as Example 1, the difference is that the weight ratio of the mannan-containing peptide in the mannan-peptide solution is 3 mg / ml or 5 mg / ml.

Embodiment 3

[0067] Example 3: Take 1000ml of the mannan peptide solution produced by space-induced mutagenic strains with a content of 3mg / ml and a pH of 4.0-6.0, add 0.25g of activated carbon, stir well, filter, add 0.5g of protein sugar, and add 0.1 ml, stir well, fill and seal to make α of different packaging specifications: 100ml / bottle, 250ml / bottle, 500ml / bottle, 1000ml / bottle, 2000ml / bottle, 5000ml / bottle, 10000ml / bottle, 20000ml / bottle - Mannan peptide, sterilized by flowing steam at 121°C for 30 minutes, take the commercially available veterinary ribavirin raw material according to the above amount, add 50g per 1000ml, or 100g can be prepared by γ-ray irradiation The 80-100 mesh powder should be tested for sterility, light inspection, packaging, and put into the market after passing the inspection.

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PUM

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Abstract

The invention discloses an animal medicine to prevent and treat fowl flu, which is characterized by the following: incorporating 500-5000mg alpha-mannan peptide solution per 1000ml; proceeding space embarkation for optimization alpha-hemoclastic streptococcus 33# bacterial; proceeding space mutagenesis; getting strain; using as production bacterial; proceeding one grade ferment and two grade ferment; producing mannan peptide zymotic fluid; purifying the zymotic fluid; filtering; adding proper essence and correcting agent; dissolving; formulating; stirring evenly; filtering; loading; sealing; sterilizing at hot pressure; getting ferment stock solution. This invention possesses high curative effect without drug tolerance.

Description

technical field [0001] The invention relates to a veterinary medicine, in particular to a veterinary medicine capable of preventing and treating bird flu. Background technique [0002] With the development of my country's animal husbandry industry, livestock and poultry infectious diseases have become a major problem plaguing the animal husbandry industry. Livestock and poultry immune failure and low immunity often lead to complex and changeable livestock and poultry diseases, especially the morbidity and mortality of young livestock and poultry increase year by year. Old diseases have not been eliminated and new diseases continue to appear. For example, infectious bursal disease of chickens and circovirus disease of pigs can destroy the body's immune system, resulting in repeated attacks of the body. the cost of farming. There are fewer and fewer single infections, and more and more mixed infections. Livestock and poultry digestive tract diseases also continue to occur, ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K38/16A61P31/16C12P21/02
Inventor 赵恒
Owner 西安亨通光华制药有限公司
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