Device for removing leukocytes from blood

A technology for leukocytes and equipment, applied in the field of equipment for removing leukocytes, can solve problems such as filter blockage and difficult operation
CN101610801AInactive Publication Date: 2009-12-233M INNOVATIVE PROPERTIES CO
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
3M INNOVATIVE PROPERTIES CO
Publication Date
2009-12-23
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to a device for removing leukocytes from blood, comprising a number of hollow fibres made from organic polymers, wherein the hollow fibres have a lumen and a wall enclosing the lumen with an inner lumen-side surface and an outer surface, the hollow fibres are arranged in a cylindrical housing with an inlet device and an outlet device and an external volume is formed between the hollow fibres and the housing, accessible to a fluid by means of the inlet device and the outlet device, characterised in that only the outer surfaces of the hollow fibres are accessible to a fluid, the lumina of the hollow fibres are accessible to a fluid, the arrangement of the hollow fibres has a high degree of organisation and the hollow fibres form the complement activation product C5a with a concentration of at least 10 [mu]g per m of fibre surface from organic polymers.
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Description

technical field

[0001] The invention relates to a device for removing white blood cells from blood. Background technique

[0002] Blood basically consists of plasma and cellular components. These cellular components include red blood cells (red blood cells), blood clotting cells (platelets), and white blood cells (leukocytes). White blood cells include lymphocytes, monocytes and neutrophils (neutrophils, PMN). Lymphocytes play a decisive role in specific immunity; monocytes and neutrophils are cell types involved in nonspecific immune system defense or inflammatory responses. Their task is, for example, to destroy invading microorganisms which have previously been appropriately recognized as foreign by certain endogenous proteins, ie by C3b of the complement system or by immunoglobulin IgG.

[0003] If the cell approaches an invading microorganism, the cell releases oxygen and proteases by which the microorganism is killed in order to then phagocytose it. If the reaction...

Claims

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