System and method for guiding of gastrointestinal device through the gastrointestinal tract
A gastrointestinal, gastrointestinal technology that is applied in the direction of catheters, applications, guide wires, etc., and can solve problems such as restricted tubes, discomfort, etc.
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example 1
[0087] Example 1: In Vitro Testing on Pig Intestine Segments
[0088] A wire with a diameter of 0.034 cm was used to determine the maximum force required for the guide wire to tear the intestinal wall. The bowel segment is cut on its longitudinal axis, cut open on a rigid surface and fixed. The wire is then manually pressed and pulled over the luminal (mucosal) side of the bowel segment several times with increasing manual pressure applied until maximum force is applied. No macroscopic tearing of the intestinal wall was observed.
example 2
[0089] Example 2: Pig neutralization in vivo test
[0090] A 22 m wire with a diameter of 0.034 cm was coiled and inserted into an oval guide element measuring 30 x 11 mm. The filaments consist of polyamide, while the guiding elements consist of polycarbonate. The wire is coiled onto itself such that continued pulling on its proximal end causes it to unravel in an inside-out fashion. The proximal end is fixed to the inner wall of the guide element. The guide element is provided with an outlet on one side of its longitudinal axis through which a 30 cm wire is passed and left outside the guide element.
[0091] 60 kg sows were studied after a 24 hour fast (water ad libitum).
[0092] Pigs were anesthetized as follows:
[0093] Premedication : Ketamine hydrochloride 10mg / kg+xylazine 1-2mg / kg IM
[0094] After intravenous cannulation of IV diazepam 10 mg / pig
[0095] induce : Isoflurane 5% mask
[0096] maintain : Following intubation, isoflurane 1-3% (IPPV) was deliv...
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