Antimicrobial and antidandruff composition and application thereof
A composition and compound technology, applied in the field of antibacterial anti-dandruff compositions, compositions comprising pyridinethione multivalent metal salts and alkoxy aryl amidine compounds, can solve the problems of high price, influence, limitation and the like , to achieve the effect of improving the effect
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Embodiment 1
[0036] Minimum Inhibitory Concentration Test
[0037]The in vitro bacteriological experiment is to judge the activity of the antibacterial agent by the minimum inhibitory concentration (MIC) to several bacterial species. In the experiment, several representative scalp common fungi and bacteria shown in Table 1 were selected for antibacterial test, and the growth of the control bacteria on the basal medium without any test samples was used as a reference, and the single compound or the mixture The minimum sample concentration used to inhibit the growth of bacteria on the medium is the minimum inhibitory concentration (MIC). Compare the results of using ZPT and hexamidine isethionate (HD) alone and mixing ZPT and HD in different proportions. Bacteriostatic effect. The mixing ratio of ZPT to HD varies from 1:8 to 1000:1.
[0038] The fungus culture medium that the present invention adopts is as follows:
[0039] 1. Evaluation of Candida albicans and Aspergillus niger using mod...
Embodiment 2
[0058] Embodiment 2 shampoo preparation embodiment
[0059] In this embodiment, example 1 is compared with example 2, example 3 is compared with example 4, example 5 is compared with example 6, and example 7 is compared with example 8.
[0060] Add polymers such as polyquaternium-10 or guar gum in water to wet it first, stir evenly, heat to 75°C, add surfactants of different properties such as sodium lauroamphoacetate, betaine to the system in turn , Fatty Alcohol Ether Ammonium Sulfate, Fatty Alcohol Ethoxylate Sodium Sulfate, Sodium Lauryl Sulfate, Ammonium Lauryl Sulfate, Coco Monoethanolamide or Coco Diethanolamide, Tallow Phthalamide , pearlescent paste or pearlescent diester, you can also add a small amount of zinc salt such as zinc oxide or zinc chloride and stir until the system is completely dissolved, stop heating, add a pre-dispersed acrylic polymer such as acrylic resin copolymer or carbo, the system Adjust the pH with citric acid or triethanolamine, add zinc pyri...
preparation example
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