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An interactive apparatus and method for real-time profiling of inhalation efforts

An interactive, inhaler technology, applied in the direction of inhalers, applications, respirators, etc., can solve the problems of inefficiency in disease treatment, patient injury, etc.

Active Publication Date: 2011-05-18
MANNKIND CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Improper use of these devices and poor inhalation technique may result in ineffective treatment of disease, for example, by administering lower doses of therapeutic substance or higher doses of therapeutic substance than required may cause harm to the patient

Method used

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  • An interactive apparatus and method for real-time profiling of inhalation efforts
  • An interactive apparatus and method for real-time profiling of inhalation efforts
  • An interactive apparatus and method for real-time profiling of inhalation efforts

Examples

Experimental program
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Effect test

example 1

[0076] Using an integrated training device

[0077] A 57-year-old patient with type 2 diabetes was instructed to receive inhaled insulin from a dry powder inhalation system because her hemoglobin A1c was high and considered out of control. Patients are trained to use integrated sensors such as Figure 9B device shown for inhalation. The device is given to the patient and asked to take a quick deep breath using the training device.

[0078] The data is collected on a computer and the patient can view the data on a display screen in real time. The patient's first inhalation attempt was too slow and was shown on the screen as entering the red "unacceptable zone." The patient is instructed to take another quick breath slightly faster than the first attempt. After completion of the inhalation, the graph indicates that the patient's inhalation process was acceptable, well within the green area of ​​the graph. While the patient feels at ease with the training, it becomes clear...

example 2

[0081] Use a detachable training device

[0082] A 59-year-old patient with type 2 diabetes was instructed to receive inhaled insulin from a dry powder inhalation system. Patients have requested inhalation systems for reasons of convenience. patients are trained to use Figure 9A device shown for inhalation. will be fitted with Figure 12 A similar detachable sensor device as shown is given to a patient and asked to take a quick deep breath using the training device.

[0083] The data is collected on a computer and the patient can view the data on a display screen in real time. The patient's first attempt is acceptable, as indicated by the software. While the patient feels at ease with the training, it becomes clear to use a similar device.

[0084] The patient removable sensor is removed from the dry powder inhaler. A dry powder inhaler and a cartridge filled with inhalable insulin are administered to the patient to treat the patient's diabetes. Six months after a p...

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Abstract

Described herein are interactive apparatus and methods for sensing and measuring real-time characteristic patterns of a subject's use of a dry powder inhalation system. The devices can be used in a wired or wireless communication mode to communicate with a display to assess the subject's usage of the inhalation system, to evaluate the performance of the inhalation system and / or to detect the characteristics profile of a dry powder formulation emitted from the inhalation system in use.

Description

[0001] Cross References to Related Applications [0002] This application claims priority to U.S. Provisional Patent Application No. 61 / 074,487, filed June 20, 2008, and U.S. Provisional Patent Application No. 61 / 159,052, filed March 10, 2009, the entire disclosures of which are incorporated by reference way combined here. technical field [0003] Described herein are interactive devices and methods for recording, transferring and displaying in real time key entity measurements made by a subject based on physiological conditions during inhalation. Background technique [0004] Inhaler devices are now commercially available for dispensing therapeutic substances through the respiratory tract, especially for pulmonary delivery in the treatment of localized or systemic diseases. For example, nebulizers, devices containing a propellant, and dry powder inhalers have been used to treat conditions such as asthma, respiratory infections, and systemic ailments such as diabetes. [...

Claims

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Application Information

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IPC IPC(8): A61M15/00
CPCA61M2206/10A61M2016/0027A61M2015/0025A61B5/087A61M2016/003A61M2015/0021A61M2202/064A61M2205/52A61M15/0065A61M2205/502A61M15/0021A61M15/0025A61M15/008A61M2205/3569A61M2205/3592A61M2209/086A61M2205/3375A61M2205/50A61M2230/40A61M15/00A61J1/06G06F17/00G08B21/02G09B23/28
Inventor 丹尼斯·欧文菲尔德卡尔·R·萨伊班诺特·阿达莫P·斯般瑟儿·堪赛斯考特·麦克林约翰·M·波利多洛查得·C·斯穆尼
Owner MANNKIND CORP
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