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Aconite extract-containing medicinal composition, preparation method and application thereof

A composition and extract technology, which is applied in the field of pharmaceutical compositions containing Aconitum extract, can solve the problems of Hanyuan disease not being carefully and clearly differentiated, and a systematic and complete theoretical system not being formed.

Inactive Publication Date: 2013-03-13
达吾列提别克·努尔沙汗 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] It has a long history to use the theory of ethnic medicine (including traditional Chinese medicine) to study the pathology of Hanyuan disease. However, due to the limitation of historical conditions, Chinese medicine has not made a detailed and clear distinction on Hanyuan disease, and has not formed a systematic and complete theoretical system.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Embodiment 1: get Kazakh traditional ethnic medicine resource plant Altai Aconitum, Xinjiang Aconitum, Tianshan Aconitum, Junggar Aconitum, Siberia Aconitum, Chuanconitum (Aconitum aconitum, Aconitum), Northern Aconitum (Aconitum grass), 10 parts by weight of one or two or more medicinal plants of the genus Aconitum of the family Ranunculaceae, such as Aconitum florifolius (i.e., Aconitum chinensis), pseudo-yellow-flowered aconitum, yellow-flowered aconitum, multi-rooted aconitum, and round-leaved aconitum , add water according to 10 times the weight of the traditional Chinese medicinal materials, heat to 98°C and extract with water for 30 minutes, sieve the permeate through 500 μm, add 5 times the amount of water to the medicinal residues, extract with water at 98°C for 20 minutes, and sieve through 500 μm For the permeate, the permeate obtained by the above water extraction is heated to boiling under a negative pressure of 0.07Mpa, concentrated and dried until the wate...

Embodiment 2

[0022] Embodiment 2: get Kazakh traditional ethnic medicine resource plant Altai Aconitum, Xinjiang Aconitum, Tianshan Aconitum, Junggar Aconitum, Siberia Aconitum, Chuanconitum (Aconitum Chuan, Aconitum), Northern Aconitum (Aconitum grass), 30 parts by weight of one or two or more medicinal plants of the genus Aconitum of the family Ranunculaceae, such as Aconitum florifolius (i.e., Aconitum chinensis), pseudo-yellow-flowered aconitum, yellow-flowered aconitum, multi-rooted aconitum, and round-leaved aconitum , crushed into strips and granules below 1cm, and extract 70% ethanol at 60°C for 30 minutes according to 10 times the total weight of the above-mentioned Chinese medicinal materials, pass through a 250μm sieve to obtain the permeate, and then press the above-mentioned traditional Chinese medicine 5 times the total weight of the material, take a concentration of 70% ethanol and extract it at a temperature of 60 ° C for 2 hours, pass through a 250 μm sieve, mix the permeat...

Embodiment 3

[0023] Embodiment 3: get Kazakh traditional ethnic medicine resource plant Altai Aconitum, Xinjiang Aconitum, Tianshan Aconitum, Junggar Aconitum, Siberia Aconitum, Chuanconitum (Aconitum Chuan, Aconitum), Northern Aconitum (Aconitum grass), 15 parts by weight of one or two or more medicinal plants of the genus Aconitum of the family Ranunculaceae, such as Aconitum florifolius (i.e. hollow stem Aconitum), pseudo-yellow-flowered aconitum, yellow-flowered aconitum, multi-rooted aconitum, round-leaved aconitum, etc. , broken into strips and granules below 1cm, extracted once at 85°C with 8 times the weight of Chinese herbal medicines and 5 times the amount of ethanol with a concentration of 90%, each time for 25 minutes, and the extract was passed through a 250 μm sieve. Concentrate and dry the obtained permeate until the dry matter content is greater than or equal to 90% to obtain an extract, add water to the above-mentioned alcohol-extracted Chinese medicinal residues at 8 times...

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Abstract

The invention discloses an aconite extract-containing medicinal composition, a preparation method and application thereof. The aconite extract-containing medicinal composition combines the viscera cold primordial qi theory of the six primordial qi theory of 'Kazak Medicine Introduction' which is a traditional medical theoretical basis, and has a main function of removing cold diseases. The Kazak traditional medicament aconite is selected to prepare an external preparation by mixing with white sal-ammoniac (NH4Cl) in proportion through water extraction and ethanol extraction. The preparation includes a medicinal extract and all other external preparations suitable for clinical cold inflammation prevention and treatment. The medicinal compositions has good effect of external auxiliary treatment on bone tuberculosis, scrofula, thyroiditis, rhinitis, bronchial asthma, lumbar disc hernia, rheumatoid arthritis, femoral head necrosis, hyperplasia of mammary glands, hysteromyoma, benign prostatic hyperplasia, osteocarcinoma, psoriasis and the like particularly, has the function of relieving pains and inflammation and the like. The medicinal composition has the advantages of reasonable formula, accurate curative effect, quick response, no irritation and other toxic or side effects, and convenience for preparation.

Description

technical field [0001] The invention relates to a pharmaceutical composition containing aconitum extract, its preparation method and application. Background technique [0002] The theory of Kazakh traditional medicine has a long history. During its long history of development, the ancestors of the Kazakh nation, traditional medicine workers and folk widely based on the theoretical basis of Kazakh traditional medicine. To study the pathogenic mechanism and diagnosis and treatment methods of various diseases. The book "Introduction to Kazakh Medicine" written in the 15th century AD by Kazakh medical scientist Utai Boydak Treu Habul (1388~unknown) includes Qi, function, energy (Huwat), and organs. Han Yuan Xing (Mu Xueli Ke Su Wuke) and other theories are used to conduct pathological analysis and design of medical schemes and drug diagnosis and treatment for various diseases; [0003] The traditional Kazakh national medicinal resource plant "Wubek" (Aconitum) is based on the ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/714A61P5/14A61P11/00A61P11/02A61P11/06A61P13/08A61P15/00A61P15/14A61P17/06A61P19/02A61P19/08A61P29/00A61P31/06A61P31/14A61P35/00A61P37/08
Inventor 达吾列提别克・努尔沙汗古丽孜汗・阿亚提别克波拉提・马卡比力
Owner 达吾列提别克·努尔沙汗
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