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Detection method of Chinese traditional medicine preparation of oral liquid for treating infant cough with lung heat

A detection method and technology of oral liquid, applied in the direction of medical formula, measuring device, drug combination, etc., can solve problems such as many influencing factors, inability to ensure stable and uniform product quality, and inability to control drug quality well

Active Publication Date: 2011-06-01
JIANGXI JIMINKEXIN PHARMA
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  • Abstract
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  • Claims
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Problems solved by technology

[0006] There is a quality control method in the standard WS-934(Z-196)-2001 of Xiaoer Reke Oral Liquid, which involves TLC identification and content determination of the relevant medicinal flavors in the other party, but the content determination in this method uses TLC scanning for the monarch drug Ephedra The content control of ephedrine, the active ingredient of the drug, has many influencing factors, and the reproducibility of the results is poor, and the quality of the drug cannot be well controlled, so that the stability and uniformity of the product quality cannot be well guaranteed.

Method used

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  • Detection method of Chinese traditional medicine preparation of oral liquid for treating infant cough with lung heat
  • Detection method of Chinese traditional medicine preparation of oral liquid for treating infant cough with lung heat
  • Detection method of Chinese traditional medicine preparation of oral liquid for treating infant cough with lung heat

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Effect test

Embodiment 1

[0057] Example 1 Pediatric hot cough oral liquid

[0058] Prescription: Ephedra (honey roasted) 60g, raw gypsum 200g, bitter almond 120g, forsythia 200g, rhubarb 40g, trichosanthes 120g, mulberry white bark 120g, Patrinia 200g, safflower 120g, licorice (honey roasted) 60g

[0059] Preparation method: Add ten times the amount of water for the above ten flavors, decoct three times, one hour each time, filter, combine the filtrate, concentrate under reduced pressure to a relative density of 1.10-1.20 (60°C), add ethanol to make the alcohol content reach 65%, stir well, let it stand for 24 hours, take the supernatant, recover ethanol until it has no alcohol smell. Add 400ml of water, refrigerate, filter, boil, add 150g of sucrose, stir well, add water to adjust the total amount to 1000ml, stir well, let stand, filter, pot, sterilize, and you get it.

[0060] Quality control method:

[0061] Identification: (1) Take 10ml of Xiaoer Reke Oral Solution, add concentrated ammonia test...

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Abstract

The invention provides a detection method of a Chinese traditional medicine preparation of oral liquid for treating infant cough with lung heat. In the invention, a high performance liquid chromatography is used for measuring the contents of effective components of the Chinese traditional medicines in a formula. Compared with the existing quality control method, the quality control method provided by the invention has the characteristics of high accuracy and good reproducibility. By using the method for controlling the quality of a product, the product can reach the requirements for controllable, stable and uniform quality and has stronger practicability and operability.

Description

technical field [0001] The invention relates to a detection method of a traditional Chinese medicine preparation, in particular to a detection method of a traditional Chinese medicine preparation of Xiaoerreke Oral Liquid. Background technique [0002] Xiaoer Reke oral liquid is composed of ephedra, raw gypsum, bitter almond, forsythia, safflower, licorice and other medicinal flavors. It has the effect of clearing away heat and promoting lung, reducing phlegm and relieving cough. Phlegm in the throat, fever, sore throat, thirst, and dry stool; children with acute bronchitis who see the above syndromes have a good clinical effect. [0003] Pediatric hot cough oral liquid prescription: [0004] Ephedra (honey-roasted) 60g, raw gypsum 200g, bitter almond 120g, forsythia 200g, rhubarb 40g, Trichosanthes 120g, mulberry bark 120g, Patrinia 200g, safflower 120g, licorice (honey-roasted) 60g [0005] Preparation method: Add ten times the amount of water for the above ten flavors, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/736A61P11/14G01N30/90G01N30/36A61K33/06
Inventor 邹武斌邱国萍
Owner JIANGXI JIMINKEXIN PHARMA
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