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Channel ushering drug common achyranthes-containing traditional Chinese drug composition for improving bone marrow stem cell homing

A technology of bone marrow stem cells and compositions, applied in the field of traditional Chinese medicine compositions containing Jingjing medicine Achyranthes bidentata, can solve the problems of limited self-repair, small number of BMSCs, and small number of stem cells, so as to promote bone repair and angiogenesis, The effect of delaying the progress of the disease and low price

Inactive Publication Date: 2012-04-25
INST OF CHINESE MATERIA MEDICA CHINA ACAD OF CHINESE MEDICAL SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

This invention relates to an effective treatment method that uses chinese herbs called achillea (Cynomorium songaricum) which helps heal damaged parts by stimulating new growths from existing ones. It can also help promote nerve regeneration through its ability to release nitric oxide or other substances like histamine into surrounding areas around it's own roots.

Problems solved by technology

The technical problem addressed in this patented study relates to improving the efficiency and accuracy of treatments involving bone marrow dysfunction associated with knee joint pain syndrome. Current options involve either traditional stromaferential graft techniques or mesenchymaphysevitus arthropathy transfer technique(MTA). These procedures may result in complications such as inflammations and fibrocartilage tissue formation around the damaged area during healing process. Additionally, current approaches like biological agents used alone cannot achieve complete recovery from these conditions without causing further damage.

Method used

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  • Channel ushering drug common achyranthes-containing traditional Chinese drug composition for improving bone marrow stem cell homing
  • Channel ushering drug common achyranthes-containing traditional Chinese drug composition for improving bone marrow stem cell homing
  • Channel ushering drug common achyranthes-containing traditional Chinese drug composition for improving bone marrow stem cell homing

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Example 1 Chinese medicine composition (water decoction) containing Achyranthes bidentata and its preparation method

[0022] Achyranthes 15 Astragalus 30 Angelica 15 Chuanxiong 15

[0023] Red peony 12, peach kernel 15, safflower 15, earthworm 15

[0024] Guizhi 15 Papaya 15 Clematis 15

[0025] Weigh and mix the above raw materials according to the prescription amount, add 5 times the weight of water to the raw materials, soak for 1.5 hours, decoct for 30 minutes, filter; add 3 times the weight of water, decoct for 20 minutes, filter ; Merge the two filtrates to make a water decoction.

Embodiment 2

[0026] Example 2 Chinese medicine composition (water decoction) containing Achyranthes bidentata and its preparation method

[0027] Achyranthes 10 Astragalus 15 Angelica 10 Chuanxiong 10

[0028] Red peony 6, peach kernel 10, safflower 10, earthworm 10

[0029] Guizhi 10 Papaya 10 Clematis 10

[0030] Weigh and mix the above raw materials according to the prescription amount, add 5 times the weight of water to the raw materials, soak for 1.5 hours, decoct for 30 minutes, filter; add 3 times the weight of water, decoct for 20 minutes, filter ; Merge the two filtrates to make a water decoction.

Embodiment 3

[0031] Example 3 Traditional Chinese medicine composition (water decoction) containing Achyranthes bidentata and its preparation method

[0032] Achyranthes 20 Astragalus 45 Angelica 20 Chuanxiong 20

[0033] Red peony 18, peach kernel 20, safflower 20, earthworm 20

[0034] Guizhi 120 Papaya 20 Clematis 20

[0035] Weigh and mix the above raw materials according to the prescription amount, add 7 times the weight of water to the raw materials, soak for 1 hour, decoct for 30 minutes, filter; add 5 times the weight of water for the dregs, decoct for 20 minutes, filter ; Merge the two filtrates to make a water decoction.

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Abstract

The present invention provides a channel ushering drug common achyranthes-containing traditional Chinese drug composition for improving bone marrow stem cell homing. The traditional Chinese drug composition is prepared from the following raw material drugs, wherein the raw material drugs comprise, by weight, 10-20 parts of common achyranthes, 15-45 parts of mongolian milkvetch root, 10-20 parts of angelica, 10-20 parts of szechwan lovage rhizome, 6-18 parts of red peony root, 10-20 parts of peach seed, 10-20 parts of safflower, 10-20 parts of lumbricus, 10-20 parts of cassiabarktree twig, 10-20 parts of common floweringquine fruit, and 10-20 parts of clematis chinensis osbeck. According to the present invention, the channel ushering drug common achyranthes-containing traditional Chinese drug composition of the present invention has the effect of improvement of autologous bone marrow stem cell homing so as to improve bone repair and vascular regeneration inside the femur head, and provides significant effects for delaying of disease developments of femur head necrosis and other osteoarticular diseases. In addition, the traditional Chinese drug composition has characteristics of lowtoxic and side-effects and low price.

Description

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Claims

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Application Information

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Owner INST OF CHINESE MATERIA MEDICA CHINA ACAD OF CHINESE MEDICAL SCI
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