Acid type amoxicillin and production method thereof

Abstract

The present invention provides an acid type amoxicillin and a production method thereof. The purpose of the present invention is to solve a poor dissolution rate of amoxicillin in the prior art. The acid type amoxicillin comprises amoxicillin and citric acid. The production method for the acid type amoxicillin comprises the following steps: uniformly mixing the amoxicillin and the citric acid; carrying out ultrafine grinding on the resulting mixture to obtain fine powder with a particle size of 700-900 meshes; and carrying out sub-packaging in a sterile room. The acid type amoxicillin of the present invention provides the same dissolution rate as amoxicillin sodium, and meets the solubility standard in the national pharmacopoeia. In addition, with the present invention, no three-waste pollution is generated, and the production cost is low, wherein the production cost of the acid type amoxicillin of the present invention is 2/3 of the production cost of the amoxicillin sodium.

Description

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AI Technical Summary

Benefits of technology

This new product has improved properties compared with other drugs like amoxycillins or penems because they have better water-soluble characteristics than traditional medicines made from them. It also produces less harmful chemical substances during manufacturing process instead of producing these compounds themselves.

Problems solved by technology

This patented technical solution describes how adding certain chemicals like tween-80 or polysaccharides helps improve the stability of drugs during storage at high temperatures (>50°C). However, these methods may cause harmful reactions when administering them through injection due to their hydrolysis properties. Therefore there needs an improved way to make this type of drug safer while maintaining effective action over time.

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