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A titanium alloy, anti-infection technology, applied in the field of anti-infective medical titanium alloy, can solve problems such as bacterial infection
Active Publication Date: 2013-02-20
SUZHOU SILVAN MEDICAL DEVICE CO LTD
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Solve the problems of bacterial infection caused by the implantati
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Embodiment 1
[0016] Different contents of copper are added to medical Ti-6Al-4V, which is currently widely used clinically. The chemical composition is (weight)%, Ti: balance; Cu: 1-10; Al: 6; V: 4, and adopt Different heat treatment processes were used for antibacterial heat treatment, see Table 1 for details. The obtained anti-infective medical Ti-6Al-4V was tested for antibacterial performance and biosafety performance, and the results are shown in Table 1.
[0017] Calculate the bactericidal rate of anti-infective medical titanium alloys against common bacteria (Escherichia coli, Staphylococcus aureus, etc.) according to the following formula:
[0018] Bactericidal rate (%) = [(number of live bacteria in control sample - number of live bacteria in anti-infection titanium alloy) / number of live bacteria in control sample]×100
[0019] In the formula, the number of viable bacteria in the control sample is the number of viable bacteria on the control sample (Ti-6Al-4V), and the number of ...
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Abstract
The invention aims to provide an anti-infective medical titanium alloy. Based on the chemical components of existing medical titanium alloy Ti-6Al-4V, a proper amount of element copper is added. After a special antibacterial heat treatment, a titanium copper phase is precipitated in the substrate of the medical titanium alloy, thus endowing the medical titanium alloy an anti-bacterial infection function. The titanium alloy can be widely applied to various titanium alloy medical equipment used in departments of orthopedics, stomatology and other medical clinical fields, thus solving the problems of bacterial infection and the like caused by implantation of medical titanium alloy medical equipment in current clinical practice.
Description
technical field [0001] The invention relates to the field of medical titanium alloy materials, in particular to an anti-infection medical titanium alloy. Background technique [0002] With its excellent biocompatibility, corrosion resistance and comprehensive mechanical properties, medical titanium alloys have been widely used in the production of various orthopedic and stomatological medical devices, such as artificial joints (knees, knees, shoulders, ankles, elbows, wrists, etc.) , finger joints, etc.), bone trauma products (intramedullary nails, steel plates, screws, etc.), orthopedic implant products such as spinal orthopedic internal fixation systems, and orthodontic products (brackets, belt rings, orthodontic archwires, anchorage with implants), etc. Ti-6Al-4V and Ti-6Al-7Nb are typical medical titanium alloys currently used clinically. [0003] However, as a common postoperative complication, bacterial infection caused by medical devices has become one of the import...
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