Acute B-lymphoblastic Leukemia Initiation Cell Characterization System

Abstract

The invention relates to designs of an acute B lymphocytic leukemia initiating cell characteristic determination system and an acute B lymphocytic leukemia initiating cell characteristic determination method. The system structure comprises a flow cytometry, data analysis software, a master computer unit, a system management module storing a master program, a monitoring and control display with a buffer, a module used for storing experience data, a scratchpad module, an operation panel, a communication module with communication protocol and data mode, a printer, an interface circuit, a test window for sampling of flow cytometry and laser scanning; a special sample tube, and a special kit. The operation method designed for the system is specifically shown in the master control program of the management module.

Description

technical field [0001] The invention belongs to detection equipment and operation technology of cell phenotype, in particular to special equipment and method for determining the characteristic of acute B lymphocytic leukemia starting cells. Background technique [0002] Flow cytometry analysis has become the method of choice for the assessment of immunophenotypic characteristics. The monoclonal immune antibody of the important staining agent has been commercialized, and there are many varieties to choose from. Immunophenotyping has provided a powerful tool for basic theoretical research. [0003] Acute lymphoblastic leukemia (ALL) is a malignant tumor of the hematopoietic system, characterized by malignant proliferation of the immature lymphatic system and immune disorders. In the past ten years, although the diagnosis and treatment of ALL have made significant progress, a large proportion of patients can achieve complete remission (Complete Remission abbreviated as CR), b...

AI Technical Summary

Problems solved by technology

However, in order to distinguish the LICs of B-ALL patients from the normal B progenitor cells, the analysis report of the LICs surface markers that must be carried out is the cutting-edge topic of laboratory medicine at present.

Moreover, in the phenotypic marker experiment, the accuracy of the preparation work and the requirements for the operation technology and process steps are extremely strict, which is also very difficult for professional researchers.

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