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Classification-model building method and device

A classification model and method establishment technology, applied in the field of life sciences, can solve the problems of high cost and low accuracy, and achieve the effect of improving accuracy, reducing cost, and solving high cost

Inactive Publication Date: 2013-09-18
NAT UNIV OF DEFENSE TECH
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Problems solved by technology

[0010] The present invention provides a method and device for establishing a classification model to at least solve the problems of high cost and low accuracy in analyzing the regulatory relationship between protein pairs based on biological experiment data in the related art

Method used

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  • Classification-model building method and device
  • Classification-model building method and device
  • Classification-model building method and device

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Embodiment Construction

[0029] Hereinafter, the present invention will be described in detail with reference to the accompanying drawings and in conjunction with embodiments. It should be noted that the embodiments in the present application and the features of the embodiments may be combined with each other in the case of no conflict.

[0030] In the following description, unless otherwise indicated, various embodiments of the present application will be described with reference to symbolic representations of acts and operations performed by one or more computers. Among them, computers include various products such as personal computers, servers, and mobile terminals, and devices with processing chips such as CPUs, single-chip computers, and DSPs can be called computers. Thus, it will be appreciated that such acts and operations, which are sometimes referred to as computer executions, include the manipulation of electrical signals that represent data in a structured form by a processing unit of a co...

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Abstract

The invention discloses a classification-model building method and device. The classification-model building method comprises the following steps: building a standard data set of the regulation-control relation between each pair of proteins; in the standard data set, acquiring a plurality of function annotation items contained by the pair of proteins; classifying the standard data sets according to an activation regulation-control relation and / or an inhibition regulation-control relation: respectively performing concentration significance analysis to the function annotation items in all classes, and building a classification model according to the analysis results. According to the technical scheme provided by the invention, the cost in researching the regulation-control relations between the pairs of proteins is reduced, and the accuracy of the researching result is improved.

Description

technical field [0001] The invention relates to the field of life sciences, and in particular, to a method and device for establishing a classification model. Background technique [0002] At present, the rapid development of high-throughput experimental technology has generated large-scale, multi-species protein interaction data, and many researchers are committed to studying the above-generated data in order to better understand the function of proteins. The basic units of proteins are domains, and interactions between proteins are usually mediated by domains. Therefore, it is particularly important to analyze protein interactions from a domain perspective. [0003] In protein interaction networks, interactions can often be assumed to be directionless. In fact, in a variety of biological networks such as signal transduction, transcriptional regulation, cell cycle or metabolic pathways, there are extensive regulatory relationships between interacting proteins, such as act...

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Application Information

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IPC IPC(8): G06F19/12
Inventor 刘伟宫二玲孙志强谢红卫
Owner NAT UNIV OF DEFENSE TECH
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