The invention discloses a manufacturing process for a copper-nickel compensating conductor alloy wire, and relates to the technical field of alloy wire processing. The manufacturing process includes the steps of main material selection, ingot casting refining, forging and hot rolling, cold wire drawing, heat treatment, finished product inspection and storage. The manufacturing process has the beneficial effects that the method that reasonable processing equipment is supplemented by corresponding process parameter selection for processing and preparing the copper-nickel alloy wire is determined, the measureable temperature interval of the prepared copper-nickel alloy wire is 0-100 DEG C, a nickel-chromium or nickel-silicon alloy wire on the market can be effectively replaced, manufacturing cost is low, measuring is accurate, stability performance is high, the problem that the alloy wire is high in manufacturing cost in the prior art is effectively solved, and application and popularization are facilitated.