Multispectral fluorescence three-dimensional tomography method and device

A tomography, fluorescence three-dimensional technology, applied in fluorescence/phosphorescence, diagnosis, diagnostic recording/measurement, etc., can solve problems such as poor accuracy and authenticity, limit the application of multispectral fluorescence 3D tomography methods, etc., to achieve accuracy and authenticity The effect of good sex and simple operation

Inactive Publication Date: 2013-10-23
RAYCO SHANGHAI MEDICAL PROD
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Problems solved by technology

However, the 3D fluorescence image obtained based on this method requires multiple 3D fluorescence image reconstruction calculations,

Method used

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  • Multispectral fluorescence three-dimensional tomography method and device
  • Multispectral fluorescence three-dimensional tomography method and device
  • Multispectral fluorescence three-dimensional tomography method and device

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Embodiment Construction

[0038] The following introduces some of the possible embodiments of the present invention, which are intended to provide a basic understanding of the present invention, but are not intended to identify key or decisive elements of the present invention or limit the scope of protection. It is easy to understand that, according to the technical solution of the present invention, those skilled in the art may propose other alternative implementation manners without changing the essence and spirit of the present invention. Therefore, the following specific embodiments and drawings are only exemplary descriptions of the technical solution of the present invention, and should not be regarded as the entirety of the present invention or as a limitation or restriction on the technical solution of the present invention.

[0039]The applicant's research found that in the method of realizing multispectral fluorescence 3D tomography based on spectral separation processing of 2D fluorescence i...

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Abstract

The invention provides multispectral fluorescence three-dimensional tomography method and device and belongs to the technical field of molecular imaging. The method includes: acquiring a multispectral fluorescence image from a target living body, subjecting the data of the multispectral fluorescence image to multispectral fluorescence three-dimensional optical tomography calculation and analysis in order to reconstruct a three-dimensional fluorescence image on the basis of original fluorescence spectra of multiple fluorescent reagents used in the target living body. The device allows for 3D imaging by the multispectral fluorescence three-dimensional tomography method, is fine in accuracy and reality of 3D fluorescence images and is simple for users to operate during the process of 3D tomography.

Description

technical field [0001] The invention belongs to the technical field of molecular imaging, and relates to Fluorescence Molecular Tomography (FMT), in particular to a method for performing three-dimensional tomography (3D tomography) based on multispectral fluorescence images without using a multispectral unmixing process (unmixing process). and its devices. Background technique [0002] Non-invasive molecular or cellular-level imaging research is revolutionizing the biological understanding of normal and diseased tissues, and plays an important role in the fields of gene therapy, immunology, drug discovery, and cancer research and treatment. effect. Among them, in vivo fluorescence imaging technology uses excitation light of a specific wavelength to excite fluorescent molecules to produce fluorescence, and provides target position information (such as depth information) and imaging of the target through image reconstruction. This imaging technology is gradually becoming matu...

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Application Information

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IPC IPC(8): A61B5/00G01N21/64
Inventor Y.戈立克王芳林杨敏
Owner RAYCO SHANGHAI MEDICAL PROD
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