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Non-small cell lung cancer brain metastases prediction device

A technology of non-small cell lung cancer and prediction device, which is applied in table lookup devices, instruments, computers, etc., can solve the problem of rare research on lung cancer specific organ metastasis prediction.

Inactive Publication Date: 2013-11-27
ZHEJIANG CANCER HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are few studies on the prediction of specific organ metastasis of lung cancer

Method used

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  • Non-small cell lung cancer brain metastases prediction device
  • Non-small cell lung cancer brain metastases prediction device
  • Non-small cell lung cancer brain metastases prediction device

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] see figure 1 , the device of the present invention is composed of the first concentric circle I, the second concentric circle II, the third concentric circle III, the fourth concentric circle IV, the fifth concentric circle V and the indicator needle VI, the first concentric circle I, the second concentric circle Ⅱ. The third concentric circle III, the fourth concentric circle IV, the fifth concentric circle V and the indicator needle VI are fixed together by metal rivets at the same center to form a compass shape. The radius of each concentric circle starts from the first concentric circle I. The fifth concentric circle V is 1cm, 2cm, 3.5cm, 4.8cm, and 6cm, respectively. The indicator needle VI rotates in a circle, and the fingertip of the indicator needle VI is located in the fifth concentric circle V, on the surface of the first concentric circle I along the longitudinal direction. The axis has a center line, the first concentric circle I is divided into half, and t...

Embodiment 2

[0021] Overall use method: Step 1: According to the routine pathology report after non-small cell lung cancer surgery, choose the semicircle of squamous cell carcinoma or semicircle of adenocarcinoma on the compass.

[0022] Step 2: Use the arrows to rotate, according to the degree of differentiation (highly differentiated; poorly differentiated), the number of lymph node metastasis (N0: no metastasis; N1: 1~3 metastasis; N2: >4 metastases), NSE status (E0: 60 ng / ml) to indicate the corresponding numbers.

[0023] The third step: directly read the number on the compass, that is, the risk percentage of brain metastases within 3 years of non-small cell lung cancer.

Embodiment 3

[0025] Specific example 1, a 65-year-old male patient underwent left upper pulmonary sleeve resection + systematic lymph node dissection in the Thoracic Surgery Department of Zhejiang Cancer Hospital in 2011. Postoperative pathological report: 1. Nodular type of left upper lung (tumor 3.5*1.2*1CM) poorly differentiated squamous cell carcinoma, mixed subtype with bronchioloalveolar carcinoma with partial area squamous cell carcinoma, reciprocating the visceral pleura. 2. (Bronchi root of right upper lobe) 1 / 5, (right upper bronchus next to bronchus) 2 / 4, (under carina) 1 / 5, (upper mediastinum) 5, (under carina) 5, (Hilar) One lymph node had chronic inflammation with carbon deposition in some lymph nodes. Immunohistochemical detection of monoclonal antibodies and oncogenes: P53(++)CerbB-2(++)ToPoII(scattered+)MRP(++). Remarks: The bronchial margins were negative. According to the postoperative pathological report of the patient, the clinician selects the semicircle of squamous...

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Abstract

The invention provides a non-small cell lung cancer brain metastases prediction device which consists of five concentric circles and a pointer with an arrow, wherein the five concentric circles and the pointer are fixed through metal rivets by sharing the same center to form a compass shape; postoperative pathological parameters of tumor patients, such as tumor types, differentiation degree and lymph gland states, are respectively marked on the concentric circles. The risk of non-small cell lung cancer brain metastases is evaluated by utilizing the state of a tumor marker NSE. The device is reasonable in design, is displayed in an intuitive compass form, and can be used for guiding a clinicist to estimate the prognostic risk of brain metastases of the patient, perform early interventional treatment on a patient with high risk and select an optimal comprehensive treatment scheme for the patient; meanwhile, the postoperative monitoring strategy can be perfected, the reexamination frequency is increased, the brain imaging check is emphasized, and the device provides help for timely discovering the brain metastases.

Description

technical field [0001] The invention belongs to the field of biological applications, and relates to a device for predicting brain metastasis of non-small cell lung cancer, which is established by analyzing the relevant pathological and tumor marker factors affecting brain metastasis by using the time data of brain metastasis after non-small cell lung cancer surgery. Transfer the risk prediction model and express the model in the form of an intuitive compass, providing simple and direct clinical application. Background technique [0002] Lung cancer is the most common malignant tumor in the world today, its incidence rate is increasing year by year, and it is the first cause of malignant tumor death. 80% of lung cancers are non-small cell lung cancer (NSCLC), of which 31-44% are locally advanced NSCLC, that is, stage IIIA and stage IIIB non-small cell lung cancer with tumor limited to the chest without clinical or pathological distant metastasis (N2 , N3 and T4 with contral...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06C3/00
Inventor 苏丹马胜林毛伟敏郑伟慧伍少远
Owner ZHEJIANG CANCER HOSPITAL
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