The invention provides a positive risk prediction method and apparatus for prostate aspiration biopsy, which can predict the specific risk of the prostate aspiration biopsy positive so as to reduce the unnecessary clinical prostate biopsy. The positive risk prediction method of the prostate aspiration biopsy comprises the following steps: acquiring the age of a prostate cancer screening patient subjected to the prostate aspiration biopsy, a value of total prostate specificity antigens, a value of free prostate specificity antigen and a value of prostate volume, substituting the acquired data into the following equation, and solving a prostate aspiration biopsy positive risk prediction value of the patient, Logit(P)=ln(P/(1-P))=a+b*Age+c*tPSA+d*fPSA-e*PV, wherein P is the prostate aspiration biopsy positive risk prediction value greater than 0 and less than 1, Age is the age of the patient, tPSA is the total prostate specificity antigen, fPSA is the free prostate specificity antigen, PVis the prostate volume, and a, b, c, d and e are constants.