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Nerve block medicinal composition

A technology of nerve block and composition, which is applied in the direction of drug combination, active ingredients of heterocyclic compounds, and pharmaceutical formulations. Effects of narcotic drug toxicity

Inactive Publication Date: 2014-06-25
王寿世
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Nerve block anesthesia is the most commonly used method of anesthesia in clinical anesthesia, especially in primary hospitals. Most of the drug formulas use simple local anesthetics, such as lidocaine, bupivacaine, ropivacaine, etc. The most widely used clinical formula is 0.75 % ropivacaine 10ml, 0.9% normal saline 15ml, but nerve block requires anesthesiologist to use anesthesia puncture needle to find abnormal sensation in the nerve root based on clinical experience and anatomical landmarks, which is easy to damage the nerve; and simple high-concentration local anesthetic is easy radiculotoxic reaction

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] A nerve blocking pharmaceutical composition, consisting of the following components in volume fraction:

[0013] 0.75% ropivacaine 10ml, dexamethasone 2ml, 0.9% normal saline 13ml.

Embodiment 2

[0015] A nerve blocking pharmaceutical composition, consisting of the following components in volume fraction:

[0016] 0.75% ropivacaine 10ml, methylprednisolone 2ml, 0.9% normal saline 13ml.

Embodiment 3

[0018] A nerve blocking pharmaceutical composition, consisting of the following components in volume fraction:

[0019] 0.75% ropivacaine 10ml, prednisone hydrochloride 2ml, 0.9% normal saline 13ml.

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PUM

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Abstract

The invention relates to a nerve block medicinal composition. The nerve block medicinal composition consists of the following components in parts by volume: 10 parts of 0.75 percent ropivacaine, 2 parts of glucocorticoid and 13 parts of 0.9 percent normal saline. The nerve block medicinal composition has the advantages that dexamethasone is added into a formula, so that injuries to nerve roots and toxic reactions of local anesthetics in a puncturing process can be reduced; dexamethasone has the effects of resisting allergy, resisting angioedema and reducing the toxic reactions of local anesthetics, so that the nerve block success rate is increased, and toxic reactions are reduced.

Description

technical field [0001] The invention relates to a medical pharmaceutical composition, in particular to a nerve blocking pharmaceutical composition. Background technique [0002] Inject local anesthetics around nerve trunks, plexuses, and nodes to block their impulse conduction and anesthetize the innervated area, which is called nerve block. Nerve blocks require only one injection to obtain a larger area of ​​anesthesia. However, it may cause serious complications. Therefore, it is necessary to be familiar with the local anatomy, understand the tissue that the puncture needle will pass through, and the nearby blood vessels, organs, and body cavities. Commonly used nerve blocks include interstitial, infraorbital, sciatic, and digital (toe) nerve trunk blocks, cervical plexus, brachial plexus blocks, and stellate ganglion and lumbar sympathetic ganglion blocks for diagnosis and treatment. [0003] Nerve block anesthesia is the most commonly used method of anesthesia in clini...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/573A61P23/00A61K31/445
Inventor 王寿世宋婷婷
Owner 王寿世
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