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Blood coagulation analyzer and blood coagulation analyzing method

A technology of blood coagulation and analysis device, which is applied to measurement devices, analysis materials, and material analysis by optical means, etc., can solve the problems of inability to obtain coagulation time, the decline of the accuracy of the judgment line, and the decline of the judgment accuracy of the coagulation time.

Inactive Publication Date: 2014-09-10
SYSMEX CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in this method, a large number of samples must be collected in order to improve the accuracy of the judgment line. On the contrary, if the number of samples is small, the accuracy of the judgment line will decrease, the judgment accuracy of the coagulation time will decrease, and the correct coagulation time cannot be obtained. And other issues

Method used

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  • Blood coagulation analyzer and blood coagulation analyzing method
  • Blood coagulation analyzer and blood coagulation analyzing method
  • Blood coagulation analyzer and blood coagulation analyzing method

Examples

Experimental program
Comparison scheme
Effect test

no. 1 approach 〉

[0116] figure 1 It is a perspective view of the appearance structure of the blood coagulation analysis device 1 .

[0117]The blood coagulation analysis device 1 has the following parts: a measurement unit 2 for optically measuring components contained in a sample (plasma), a sample transport unit 3 arranged in front of the measurement unit 2, and analysis of measurement data obtained by the measurement unit 2 and A control device 4 that issues instructions to the measurement unit 2 .

[0118] The measuring unit 2 is provided with covers 2a, 2b, a cover 2c, and a power button 2d. After the user opens the cover 2a, it can be placed on the reagent table 11, 12 (refer to figure 2 ) reagent container 103 is replaced with a new reagent container 103 or another reagent container 103 is added. The reagent container 103 has a barcode label 103a printed with a barcode including the type of the contained reagent and a reagent ID consisting of the serial number of the reagent.

[01...

no. 2 approach 〉

[0207] In the first embodiment described above, when it is judged that the blood coagulation reaction has not occurred during the measurement time T1, the Figure 9 In the interface shown, the measurement results are hidden. In the present embodiment, when it is judged that the blood coagulation reaction has not occurred within the measurement time T1, an instruction is further accepted as to whether or not to re-measure. After the user inputs an instruction for re-measurement, the blood coagulation analysis device 1 performs re-measurement on the samples judged to have no blood coagulation reaction, and calculates the prothrombin time (PT). Here, the measurement time T2 for the re-measurement is set to a value greater than the measurement time T1 for the initial measurement (for example, T2=2×T1 ).

[0208] In this embodiment, in order to enable re-measurement, a little more sample is dispensed from the sample container 101 to the empty cuvette 104 on the cuvette table 13 . ...

no. 3 approach 〉

[0222] In the second embodiment, if it is judged that the blood coagulation reaction has not occurred, it waits for an instruction from the user and performs remeasurement. In contrast, in the present embodiment, when it is judged that the blood coagulation reaction has not occurred, remeasurement is automatically performed.

[0223] Figure 14 It is a flowchart of the prothrombin time (PT) measurement process in this embodiment. exist Figure 14 In the steps S11~S16 and S21, S22 of Figure 12 The corresponding steps are processed in the same way.

[0224] After the control device 4 receives the measurement result of the initial measurement from the measurement unit 2 (S21), it implements Figure 8 Analysis process shown in B (S22). Next, the control device 4 judges whether or not the remeasurement has been performed ( S41 ), and if the remeasurement has not been performed ( S41 : No), it judges whether or not a flag has been set in the analysis process ( S22 ) ( S42 ). ...

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Abstract

In order to improve accuracy of determination of a blood coagulation time without requiring complicated work, a measurement unit 2 of a blood coagulation analyzer 1 irradiates a measurement specimen prepared by mixing a blood specimen and a reagent together, with lights of a plurality of wavelengths including light of a wavelength »1 and light of a wavelength »2, obtains information regarding an amount of transmitted light that transmits through the measurement specimen, and transmits the obtained information to a control device 4. The control device 4 calculates a blood coagulation time of the blood specimen based on information regarding a transmitted light amount based on light of the wavelength »1. Moreover, the control device 4 determines whether a blood coagulation time can be appropriately obtained through the measurement, based on information regarding transmitted light amounts based on light of wavelength »1 and light of wavelength »2.

Description

technical field [0001] The present invention relates to a blood coagulation analysis device and a blood coagulation analysis method which mix a reagent into a blood sample and analyze blood coagulation. Background technique [0002] As a method for detecting blood coagulation, there is a method of measuring coagulation by mixing sample plasma and a coagulation reagent, known methods include a scattered light detection method and a transmitted light detection method. For example, Japanese Patent Laid-Open (Japanese Patent Laid-Open) No. 2010-217059 discloses a blood coagulation analysis device using scattered light detection. In this blood coagulation analysis device, the value of the scattered light quantity is obtained at regular time intervals by the measurement unit, and the point at which coagulation ends is detected based on the time-dependent change in the scattered light quantity value after adding a certain reagent to the blood sample. Then take the time point when ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/31
CPCG01N33/4905G01N21/3151G01N33/86
Inventor 山口圭一竹内康浩黑野浩司
Owner SYSMEX CORP
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