Sarcopyramis nepalensis extract and application thereof

A technology of mulberry and extract, applied in the field of chemistry, can solve the problems of little research on the chemical composition of mulberry, biological activity and the like

Inactive Publication Date: 2015-07-29
王燕燕
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] One of the purposes of the present invention is to provide a kind of Chutouhong extract and application thereof

Method used

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  • Sarcopyramis nepalensis extract and application thereof
  • Sarcopyramis nepalensis extract and application thereof
  • Sarcopyramis nepalensis extract and application thereof

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Embodiment Construction

[0019] The present invention will be described in detail below in conjunction with specific embodiments. It should be noted that the technical features or combinations of technical features described in the following embodiments should not be regarded as isolated, and they can be combined with each other to achieve better technical effects.

[0020] The invention provides an extract of Chutouhong. The whole herb of Chutouhong is taken, crushed, extracted with 95% ethanol six times, each time for 1 week, filtered and concentrated to obtain an extract.

[0021] Take the extract and dilute with water, sequentially extract with petroleum ether, ethyl acetate and n-butanol to obtain petroleum ether extract, ethyl acetate extract, n-butanol extract and water-soluble matter;

[0022] The petroleum ether extract was chromatographed on a silica gel column, eluted with a petroleum ether-ethyl acetate system gradient, separated and purified, and recrystallized to obtain Compound 3, Compo...

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Abstract

The invention discloses a sarcopyramis nepalensis extract. A preparation method of the sarcopyramis nepalensis extract comprises the following steps: taking whole herb of sarcopyramis nepalensis; after crushing the taken whole herb of the sarcopyramis nepalensis, extracting the crushed whole herb of the sarcopyramis nepalensis with ethyl alcohol of 95% for six times, wherein the extraction time each time is one week; performing the filtration, and performing the concentration so as to obtain a medicinal extract. The extract can be used for medicines for nourishing a liver and reducing transaminase, the sarcopyramis nepalensis extract disclosed by the invention can widely affect all the cytokine levels, pharmacological activities of nourishing the liver and reducing the transaminase are realized through regulating the balance of a cytokine network, and scientific basis is provided for the clinical application of the sarcopyramis nepalensis extract.

Description

technical field [0001] The invention belongs to the field of chemistry, and in particular relates to an extract of Chutouhong and its application. Background technique [0002] Sarcopyramis nepalensis Wall., also known as Sarcopyramis nepalensis Wall., also known as Sarcopyramis nepalensis Wall., belongs to Sarcopyramis Wall1 in the family Melastomaceae. It is mainly distributed in Sichuan, Yunnan, Hubei, Guangxi, Guangdong, Jiangxi, Taiwan, Fujian and other places in Southeast Asia and my country. According to the "Chinese Medicine Dictionary", the whole herb of Chutouhong can be used medicinally. It has the effect of clearing heat and detoxifying, clearing liver and purging fire, and it is the best medicine for treating acute hepatitis, cough due to lung heat, snake head boil, unknown swelling poison, gastroenteritis and other diseases. Rare and valuable Chinese herbal medicine. It has the best curative effect on acute hepatitis (hepatitis A and hepatitis B in the acute ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C07J9/00C07J17/00C07D311/30C07D311/40C07C69/732C07C53/126C07C65/03C07C65/05C07D305/08C07C47/58C07J63/00C07C59/52C07C57/12C07H3/02C07H3/04C07D309/32C07H3/08A61K31/352A61K31/216A61K31/20A61K31/192A61K31/575A61K31/337A61K31/11A61K31/56A61K31/201A61K31/7004A61K31/7016A61K31/351A61K31/704A61P1/16
CPCC07D311/30C07C47/58C07C53/126C07C57/12C07C59/52C07C65/03C07C65/05C07C69/732C07D305/08C07D309/32C07D311/40C07H3/02C07H3/04C07H3/08C07J9/00C07J17/005C07J63/008
Inventor 王燕燕张勇慧韩师师汪海斌袁健群张雨薇
Owner 王燕燕
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