Microfluidic chip droplet generation device

A microfluidic chip and droplet generation technology, applied in laboratory utensils, laboratory containers, chemical instruments and methods, etc., can solve the problems of complex control process and many control droplet generation devices, and achieve the generation conditions. Simple, small device size, easy to carry

Active Publication Date: 2015-11-04
HEBEI UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The equipment in this application requires the upper computer to issue control commands through the serial port, and control four solenoid valves and plunger pumps to realize air intake and air outlet to realize oil and water injection. There are many droplet generation devices in the entire control, and the control process is relatively complex

Method used

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  • Microfluidic chip droplet generation device
  • Microfluidic chip droplet generation device
  • Microfluidic chip droplet generation device

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Embodiment 1 (see figure 1 )

[0023] All the effusion bottles are cylindrical bottles with an inner diameter of 16mm, an outer diameter of 20mm, and a height of 30mm. They are placed independently, and the applied DC voltage is 0-30V. The first electrode 1 and the second electrode 7 are both graphite electrodes. The first electrode 1 is connected to the positive pole of the DC power supply, and the second electrode 7 is connected to the negative pole of the DC power supply. When the DC power supply is powered on, the saturated salt water in the first reaction liquid accumulation bottle 2 is electrolyzed to generate chlorine gas, which enters the oil storage liquid accumulation bottle 4 through the first pressure valve 3, and the dimethyl in the oil storage liquid accumulation bottle 4 The silicone oil is pressed into the oil channel of the microfluidic chip 9, and at the same time, the saturated salt water in the second reaction liquid accumulation bottle 6 is electro...

Embodiment 2

[0024] Embodiment 2 (see figure 2 )

[0025]All effusion bottles are cuboids with a bottom surface of 25mm×25mm and a height of 20mm. All effusion bottles are placed side by side to form a 1×4 pattern, resulting in a cuboid structure with a size of 100mm×25mm×20mm; the applied DC voltage is 0-30V , the first electrode 1 and the second electrode 7 are pencil leads, the first electrode 1 is connected to the positive pole of the DC power supply, and the second electrode 7 is connected to the negative pole of the DC power supply. Distilled water is housed in the water storage liquid accumulation bottle 5, and simethicone oil is housed in the oil storage liquid accumulation bottle 4. When the DC power supply is powered on, the saturated salt water in the first reaction liquid accumulation bottle 2 is electrolyzed to generate chlorine gas, which enters the oil storage liquid accumulation bottle 4 through the first pressure valve 3, and the simethicone in the oil storage liquid acc...

Embodiment 3

[0026] Embodiment 3 (see image 3 )

[0027] All the effusion bottles are cuboids with a bottom surface of 20mm×20mm and a height of 15mm. All the effusion bottles form a 2×2 pattern to obtain a cuboid structure with a size of 40mm×40mm×15mm; the applied DC voltage is 0-30V, the first Both the electrode 1 and the second electrode 7 are three-dimensional electrodes, the first electrode 1 is connected to the positive pole of the DC power supply, and the second electrode 7 is connected to the negative pole of the DC power supply. The three-dimensional electrode consists of an anode-graphite plate, a cathode-stainless steel plate, and powdered activated carbon as filling electrodes; distilled water is contained in the water storage liquid storage bottle 5, and dimethyl silicone oil is housed in the oil storage liquid storage bottle 4. When the DC power supply is powered on, the saturated salt water in the first reaction liquid accumulation bottle 2 is electrolyzed to generate chl...

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Abstract

The invention discloses a microfluidic chip droplet generation device. The microfluidic chip droplet generation device is characterized by comprising a first electrode, a first reaction fluid accumulating bottle, a first pressure valve, an oil storage fluid accumulating bottle, a water storage fluid accumulating bottle, a second reaction fluid accumulating bottle, a second electrode, a second pressure valve, a microfluidic chip, a CCD camera, a detection unit, an impedance meter and a pulse counter. The device utilizes a gas produced in reaction as a driving force, and has the characteristics of small volume, convenience in carrying, low cost, simplicity in operation, and capability of achieving feedback control.

Description

technical field [0001] The invention relates to the technical field of microfluidic control, in particular to a microfluidic chip droplet generating device. Background technique [0002] Microfluidic chip system (Microfluidic chip), also known as Lab on chip, integrates the functions of traditional laboratories on a chip of a few square centimeters with the help of micro-electromechanical processing technology, and then realizes sampling, separation, and reaction. , analysis and testing functions. Microfluidic chips have the advantages of less reagent consumption, high detection accuracy, and portability, and have wide applicability and application prospects. Droplet-based microfluidics (droplet-based microfluidics) is in a micro-scale channel, for two incompatible liquids (one is a continuous phase, the other is a discrete phase), using flow shear force and surface tension A technology that divides and separates fluids into discrete nanoliter to picoliter volume droplets....

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01L3/00
Inventor 李珊珊李铭浩闫姿姿张明航戴士杰李铁军
Owner HEBEI UNIV OF TECH
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