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Application of secoisolariciresinol diglucoside in preparation of drug with resistance to eimeria tenella

The technology of flax lignan and Eimeria, which is applied to the application field of flax lignan in the preparation of anti-Eimeria tenella medicines, can solve the problem that the effect of anti-Eimeria tenella cannot be inferred, There are no problems such as the anti-Eimeria tenella effect of flax lignans, and the effects of alleviating serious drug resistance problems, good resistance to Eimeria tenella, and speeding up research and development are achieved.

Inactive Publication Date: 2016-12-07
广州市汇鑫动物药业有限公司
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  • Abstract
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  • Claims
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AI Technical Summary

Problems solved by technology

[0007] Flax lignans, as a drug with antibacterial, anti-cancer and antihypertensive application prospects, have attracted much attention in recent years, but there is no report that flax lignans have anti-Eimeria tenabilis effects. Known properties cannot infer whether it has anti-Eimeria tenella

Method used

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  • Application of secoisolariciresinol diglucoside in preparation of drug with resistance to eimeria tenella
  • Application of secoisolariciresinol diglucoside in preparation of drug with resistance to eimeria tenella
  • Application of secoisolariciresinol diglucoside in preparation of drug with resistance to eimeria tenella

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Embodiment 1

[0018] Preparation of flax lignan powder: take 3 g of flax lignan (content not less than 99%) and 97 g of starch and mix well.

[0019] The usage and dosage of the powder: mix the above 100g powder into 100kg feed, and feed according to the daily food intake.

Embodiment 2

[0021] Preparation of water-soluble powder of flax lignans: take 3g of flax lignans (content not less than 99%) and 97g of glucose and mix well.

[0022] Usage and dosage of water-soluble powder: Dissolve the above-mentioned 100g powder in 200 liters of water, cut off the water for 2 hours before the medicine, and then feed according to the normal drinking water amount.

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Abstract

The invention discloses an application of secoisolariciresinol diglucoside in preparation of a drug with resistance to eimeria tenella. Powder is prepared from the secoisolariciresinol diglucoside and acceptable auxiliary materials, is added to feed and is mixed uniformly, and chickens are fed according to the daily amount of feed; or water-soluble secoisolariciresinol diglucoside powder is prepared from the secoisolariciresinol diglucoside and dissolved in water, and the chickens are fed according to the daily drinking amount. Animal infection experiments prove that the ACI (anti-coccidial index) of the secoisolariciresinol diglucoside can be up to 165 or higher, and the secoisolariciresinol diglucoside has a better eimeria tenella resistant effect. Compared with a conventional anti-coccidial drug, namely, sulfachloropyrazin, the secoisolariciresinol diglucoside has a remarkable eimeria tenella resistant effect. According to the application of the secoisolariciresinol diglucoside, the problem of severe drug tolerance produced through adoption of the anti-coccidial drug in the current breeding industry can be effectively solved, the research and development speed of a new drug can be increased on the basis, and great benefits are provided for green and healthy development of the breeding industry.

Description

technical field [0001] The invention relates to a new application of flax lignans, in particular to the application of flax lignans in the preparation of anti-Eimeria tenella medicaments. Background technique [0002] Chicken coccidiosis is the most important disease that seriously endangers the intensive chicken industry production, and the economic loss caused by it is as high as more than 2.5 billion pounds every year. Its pathogen is Eimeria spp of the apicomplexa class, The most harmful of these is Eimeria tenella. Chemical drug treatment is one of the important measures to control coccidiosis in chickens, but at present chicken coccidiosis has extensive and serious drug resistance, and new anticoccidiosis drugs are urgently needed to be put on the market. [0003] Flax lignan (Secoisolariciresinol Diglucosi), also known as secoisolariciresinol diglucoside; mainly exists in the flaxseed of the flax plant, an annual herb with a height of 30-100 cm. Stems erect, branche...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7034A61P33/02A23K20/163A23K50/75
CPCA61K31/7034
Inventor 余永鹏张玉团覃润金
Owner 广州市汇鑫动物药业有限公司
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