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Application of hexachlorophene in preparing medicine for resistance to Eimeria tenella

A technology of Eimeria and hexachlorophene, which is applied in the field of application of hexachlorophene in the preparation of anti-Eimeria tenella drugs, can solve the problem that hexachlorophene has not been seen to resist Eimeria tenella and cannot It is inferred that there are problems such as anti-Eimeria tenabilis, poor effect, etc.

Active Publication Date: 2012-05-09
广东省农业科学院兽医研究所
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Hexachlorophene has good antibacterial effect on Gram-positive bacteria, but poor effect on Gram-negative bacteria, and has no effect on Mycobacterium tuberculosis and spores
[0007] So far, there has been no report on the effect of hexachlorophene against Eimeria tenella, and it is impossible to infer whether hexachlorophene has an anti-Eimeria tenae effect based on the known properties of hexachlorophene

Method used

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  • Application of hexachlorophene in preparing medicine for resistance to Eimeria tenella
  • Application of hexachlorophene in preparing medicine for resistance to Eimeria tenella
  • Application of hexachlorophene in preparing medicine for resistance to Eimeria tenella

Examples

Experimental program
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Effect test

example 1

[0030] Preparation of powder: Mix 30g of hexachlorophene (content not less than 99%) and 70g of starch.

[0031] Usage and dosage: Make every 100 kg of feed mixed with 15 grams of the hexachlorophene, and feed according to the daily food intake.

example 2

[0033] Preparation of suspension: take 30g of hexachlorophene (content not less than 99%), add propylene glycol and stir, and dissolve to 100ml.

[0034] Usage and dosage: the suspending agent is mixed in drinking water, so that the concentration of hexachlorophene is 7.5g / 100Kg water, and then drink water according to the daily drinking water amount.

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PUM

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Abstract

The invention discloses an application of hexachlorophene in preparation of a drug resistant to Eimeria tenella. The hexachlorophene and pharmaceutically acceptable excipients are evenly mixed and added in water or feed. The animal infection experiments confirm that the anticoccidial index (ACI) of the hexachlorophene reaches over 168.8, and the hexachlorophene has better effect in resistance to the Eimeria tenella.

Description

Technical field [0001] The present invention involves a new purpose of hexide phenol, which specifically involves the application of hexide phenols in preparation of antin tender Emi Earlobe drugs. Background technique [0002] Chicken ball disease is the most important epidemic in the production of intensive chicken industry. The economic loss caused by this year is as high as more than 2.5 billion pounds. Eimeriaspp ), Of which the most harmful is the tender Emi Earlin cage ( Eimeria Tenella To.Although my country has no accurate statistics so far, the most conservative estimation of its losses should not be less than 2.5 billion yuan.Chemical drug treatment is one of the important measures to control chicken and coccida disease, but the current chicken balls are wide and serious, and the new anti -corms drugs are urgently needed. [0003] Hexachlorophene, chemical name, 2,2′-sub-armor (3,4,6-coxhenol), also known as methyl chloroltol; toxicol, etc.It is a compound with white o...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/055A61P33/02
Inventor 孙铭飞蔡建平谢明权覃宗华吕敏娜袁建丰李祥瑞吴彩艳王志军余劲术
Owner 广东省农业科学院兽医研究所
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